There are several different cytochemical stains that are commonly used in hematopathology, one of which is the non-specific esterase (or NSE) stain. Monocytes and their precursors (promonoblasts and monoblasts) stain a pretty red color with this stain.

Neuron-specific enolase (NSE) being a cytosolic marker may be useful in this setting. NSE is by many considered nonspecific, due to the finding of this marker in tumors considered not to be of neuroendocrine origin. Our aim was to determine whether this is true and whether NSE is more specific than previously realized.

Neuron-specific enolase (NSE) being a cytosolic marker may be useful in this setting. NSE is by many considered nonspecific, due to the finding of this marker in tumors considered not to be of neuroendocrine origin. Our aim was to determine whether this is true and whether NSE is more specific than previously realized.

A high serum NSE level was shown to be a significant early predictor of poor neurological outcome in the total study population, and in near-hanging patients with cardiac arrest. To our knowledge, this is the first study to analyze the relationship between serum NSE and neurological outcome in near-hanging patients.

Alpha-naphthyl butyrate esterase, also known as nonspecific esterase (NSE), is a monocytic marker (Fig. 18.10 A). This stain is helpful in distinguishing acute leukemias with monocytic differentiation, as well as histiocytic lesions. However, lymphoblasts, erythroblasts, and megakaryoblasts may also show a few punctuate cytoplasmic-positive ...

Immunohistochemical stain of INI1 in malignant rhabdoid tumor. This lesion is characterized by loss of the SMARCB1 gene, which encodes INI1 protein. This is a highly conserved gene that is critical to chromatin maintenance.

Immunocytochemical staining for neuron-specific enolase (NSE) was performed in 44 round-cell tumors from children by the improved immunoglobulin-enzyme bridge method with antiserum against NSE. The tumors studied consisted of 15 neuroblastomas showing various degrees of histologic differentiation, 1 …

As monocytes differentiated into macrophages, additional isozymes of nonspecific esterase are expressed leading to intense cytoplasmic staining. 51 Cord blood monocytes stain positive for nonspecific esterase, however, the proportion of esterase-positive cells is lower than in adult peripheral blood. 52 Peroxidase activity is also prominent in ...

2025年1月27日 · In normal tissue, most neurons and their axonal and dendritic processes stain strongly positive for Neuron Specific Enolase (NSE), with the exception of Purkinje cells. Schwann cells, cells of the adrenal medulla, and paraganglia also contain NSE.

In normal tissues, most neurons and their axonal and dendritic processes stain strongly positive for NSE, with the exception of Purkinje's cells. Schwann's cells, cells of the adrenal medulla and paraganglia also contain NSE.