Indicated for treatment of HIV-1 infection in combination with other antiretrovirals; also used for prevention of maternal-fetal HIV transmission in women with no prior antiretroviral treatment....

2003年6月6日 · In many developing countries, a two-dose regimen of nevirapine (NVP) around the time of birth is advocated as the most cost-effective way to prevent mother to child HIV transmission. One dose is taken by the mother at the onset of labour and one dose is given to her baby, between 48 and 72 hours after birth.

2024年5月8日 · Very bad and sometimes deadly liver problems have happened with nevirapine oral suspension. The chance is highest within the first 18 weeks of taking this drug, but can happen at any time. The chance is also highest in women and in people with certain CD4 counts, but can happen in men and in people with any CD4 count.

Nevirapine (NVP) is a key component of antiretroviral prophylaxis and treatment for neonates. We evaluated current WHO weight-band NVP prophylactic dosing recommendations and investigated optimal therapeutic NVP dosing for neonates.

Initial Dose (lead-in dosing period): In children up to 2 years of age, some experts start this drug without lead-in dosing. As long as there are no side effects, the mg dose does not need to be decreased when the child reaches 8 years; the mg dose is left the same to achieve the appropriate mg/m2 dosage as the child grows larger.

2023年10月16日 · Nevirapine is used to treat HIV, the virus that can cause acquired immunodeficiency syndrome (AIDS). Nevirapine is not a cure for HIV or AIDS, and should not be used to prevent HIV. Nevirapine oral solution (liquid) is for …

VIRAMUNE is the brand name for nevirapine (NVP), a non-nucleoside reverse transcriptase inhibitor with activity against Human Immunodeficiency Virus Type 1 (HIV-1). Nevirapine is...

NVP is a substrate and inducer of cytochrome P450 (CYP) 3A4 and CYP2B6. More than 80% of an NVP dose is eliminated in urine as uridine diphosphate glucuronosyltransferase (UGT)-derived glucuronidated metabolites. NVP should not be administered to patients with moderate or severe hepatic impairment.

NVP is also used for the treatment of HIV-1 infection in children and adults, in combination with other antiretrovirals. Check national recommendations. Also comes in fixed-dose combinations with other antiretrovirals.

Nevirapine (NVP) - give maintenance dose 160–200 mg/metre square per dose twice daily. Lead-in dose during week 1 and 2 give only AM dose. Lopinavir/retonavir (Lop/rit)- give 230/75.5 mg/m 2 twice daily and increased to 300/75 mg/m2 if taken with Nevirapine.