
NBQX - Wikipedia
NBQX (2,3-dioxo-6-nitro-7-sulfamoyl-benzo[f]quinoxaline) is an antagonist of the AMPA receptor. NBQX blocks AMPA receptors in micromolar concentrations (~10–20 μM) and also blocks kainate receptors .
NBQX (FG9202) | AMPA Receptor Antagonist | MCE - MCE-生物 …
NBQX (FG9202) is a highly selective and competitive AMPA receptor antagonist. NBQX has neuroprotective and anticonvulsant activity.
NBQX | AMPA Receptors - Tocris Bioscience
NBQX is a selective and competitive AMPA and kainate receptor antagonist (IC 50 = 0.15 μM and 4.8 μM, respectively). NBQX blocks the antidepressant effects of 8-Hydroxy-DPAT hydrobromide (Cat. No. 0529), decreases mTOR and BDNF levels. NBQX is neuroprotective, anticonvulsant, antinociceptive and active in vivo.
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NBQX;AMPA/海人酸拮抗剂 - 知乎 - 知乎专栏
2023年2月26日 · NBQX是一种AMPA 结合位点的有效且有鉴别力的 拮抗剂 。 该化合物具有神经保护特性。 图1.NBQX化学结构. NBQX基础信息. 中文名:AMPA拮抗剂;红藻氨酸拮抗剂; AMPA受体拮抗剂. 英文别名NBQX, AMPA / kainate antagonist. CAS号:118876-58-7
NBQX, a highly selective competitive antagonist of AMPA and KA ...
We found that only NBQX had an effect on acute seizure development, resulting in a significantly higher number of mice experiencing seizures, an increase in the number of seizures per mouse, a greater cumulative seizure score per mouse and a significantly higher mortality rate …
NBQX - an overview | ScienceDirect Topics
NBQX is a compound that shows a 30-fold greater affinity for AMPA binding compared to kainate binding, and is essentially inactive at the glycine site of the NMDA receptor. You might find these chapters and articles relevant to this topic.
NBQX(FG9202) AMPA受体拮抗剂|CAS 118876-58-7 - 翌圣生物
NBQX (FG9202) 是一种 AMPA 受体拮抗剂。 CAS号 (CAS NO.) 1. 为了您的安全和健康,请穿实验服并戴一次性手套操作。 2. 粉末溶解前请先短暂离心,以保证产品全在管底。 3. 避光干燥 …
NBQX - CAS:118876-58-7 - CAS号查询_生物试剂_化学试剂_分析 …
NBQX (FG9202) has a high affinity for AMPA and kainate binding sites with little or no affinity for the glutamate recognition site on the NMDA receptor complex.
NBQX | Purity >99% | CAS 118876-58-7 | Alomone Labs
NBQX (2,3-Dihydroxy-6-nitro-7-sulfamoyl-benzo(F) quinoxaline) is an analogue of the quinoxalinedione antagonists to the non-NMDA glutamate receptor. NBQX is a potent and selective inhibitor of binding to the quisqualate subtype of the glutamate receptor, with no activity at the NMDA and glycine site 3 .
AMPA Receptor antagonist NBQX attenuates later-life epileptic …
To determine whether AMPA receptor (AMPAR) antagonist NBQX can prevent early mTOR pathway activation and long-term sequelae following neonatal seizures in rats, including later-life spontaneous recurrent seizures, CA3 mossy fiber sprouting, and autistic-like social deficits.