2024年12月25日 · NCOA2 (Nuclear Receptor Coactivator 2) is a Protein Coding gene. Diseases associated with NCOA2 include Rhabdomyosarcoma 2 and Aneurysmal Bone Cysts. Among …

NCoA-2 is a transcriptional coregulatory protein that contains several nuclear receptor interacting domains and an intrinsic histone acetyltransferase activity. NCOA2 is recruited to DNA …

已发现该基因参与导致与各种癌症中其他基因融合的易位，包括急性髓性白血病中的赖氨酸乙酰转移酶 6A (KAT6A) 基因、急性淋巴细胞白血病中的 ETS 变体 6 (ETV6) 基因，以及他在间充质 …

2016年10月3日 · Title: Knockdown of NCOA2 Inhibits the Growth and Progression of Gastric Cancer by Affecting the Wnt Signaling Pathway-Related Protein Expression. Our results …

GSEA results and analysis of immune infiltration revealed that NCOA2 was associated with PD-1/PD-L1 expression and infiltration of other immune cells in ccRCC. Conclusions: NCOA2 has …

2019年3月18日 · As a member of the p160 steroid receptor coactivator (SRC) family, nuclear receptor coactivator 2 (NCOA2) is known to play essential roles in many physiological and …

2023年10月4日 · Forced expression of PGC-1α in Ncoa2fl/fl/CD4Cre CD8+ T cells restored mitochondrial function, T-cell activation, IFNγ production, and antitumor immunity. This work …

Enables several functions, including RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; chromatin binding activity; and nuclear receptor coactivator …

Here, we show that Ncoa2 promotes CD8+ T cell–mediated immune responses against tumors by stimulating T-cell activation via upregulating PGC-1α expression to enhance mitochondrial …

Nuclear receptor coactivator 2 is a protein in humans that is encoded by NCOA2 gene. Transcriptional coactivator for steroid receptors and nuclear receptors. Coactivator of the …