NEUROG2 Gene - GeneCards | NGN2 Protein | NGN2 Antibody
2024年12月25日 · NEUROG2 (Neurogenin 2) is a Protein Coding gene. Diseases associated with NEUROG2 include Neuropathy, Hereditary Sensory And Autonomic, Type Iii and Pervasive …
Neurogenin-2 - Wikipedia
Neurogenin-2 is a protein that in humans is encoded by the NEUROG2 gene. [5] Neurogenin-2 is a member of the neurogenin subfamily of basic helix-loop-helix transcription factor genes that …
NEUROG2 neurogenin 2 [Homo sapiens (human)] - Gene - NCBI
2025年1月4日 · Grafted human embryonic progenitors expressing neurogenin-2 stimulate axonal sprouting and improve motor recovery after severe spinal cord injury. Perrin FE, et al. PLoS …
Neurog2 directly converts astrocytes into functional neurons …
2021年3月1日 · In the midbrain, Neurog2-induced neuronal cells (Neurog2-iNs) exhibit neuronal morphology, mature electrophysiological properties, glutamatergic identity (about 60%), and …
NEUROG2 regulates a human-specific neurodevelopmental gene …
2024年1月11日 · Mining single cell data from cerebral organoids and human fetal cortices, we found that NEUROG2 expression is enriched in basal neural progenitor cells. To identify and …
Proneural factors Ascl1 and Neurog2 contribute to neuronal …
2019年5月13日 · Using direct neuronal programming of embryonic stem cells, we found that two main vertebrate proneural factors, Ascl1 and neurogenin 2 (Neurog2), induce different …
Neurog2 directly converts astrocytes into functional neurons in ...
2021年3月1日 · In the spinal cord, astrocytes from both the intact and lesioned sources could be converted into functional neurons with ectopic expression of Neurog2 alone. Notably, further …
Neurog2 simultaneously activates and represses alternative gene ...
By comparing the activities of transcriptional activator (Neurog2-VP16) and repressor (Neurog2-EnR) fusions to wild-type Neurog2, we first demonstrate that Neurog2 functions as an activator …
Examining the NEUROG2 lineage and associated gene expression …
2025年1月15日 · Using ChIP-qPCR, gene silencing and overexpression studies in COs, we show NEUROG2 is necessary and sufficient to directly transactivate known target genes …
Multimodal profiling of the transcriptional regulatory landscape of …
2022年2月7日 · In addition, we functionally demonstrate a new role for Neurog2 in directly mediating enhancer activity, DNA demethylation, increasing chromatin accessibility and …