活化T细胞核因子2可抑制高迁移率蛋白1的释放 - j-smu.com
The effect of LPS stimulation on NFAT2 and HMGB1 interaction in the cytoplasm was observed by immunoprecipitation assay. HMGB1 production and release was detected in cells with …
The mechanism of the NFAT transcription factor family involved in ...
2022年11月3日 · In a mouse model of LPS-induced acute lung injury, ROS produced by NOX2 promoted stromal interaction molecule1 dependent (STIM1-dependent) cytosolic Ca 2+ …
一文搞定|活化的T细胞核内因子 (NFAT)的结构及其功能 - 知乎
活化的T细胞核内因子（Nuclear Factors of activated T cells， NFAT）是一类 转录因子 家族，最初是在活化的T细胞中作为一种能够结合在人白介素-2（Interleukin-2，IL-2）的启动子上的快 …
Immunity：朱书/潘文团队揭示肠道细菌代谢产物的促癌机制_澎湃 …
2024年3月13日 · 活化T细胞核因子2（NFAT2）是一种Ca2+依赖的转录因子，调节直接指导CD8+ T细胞效应功能的基因表达。 磷酸化形式（不活跃）的NFAT2位于细胞质中。 在T细胞受 …
A Cell Permeable Peptide Inhibitor of NFAT Inhibits Macrophage …
VIVIT attenuated LPS or LPS plus IFN-γ induced IL-12 p40 mRNA and protein expression in bone marrow derived macrophages (BMDMs) and reduced DNA binding of NFAT to a composite …
Calcineurin/NFAT signaling and innate host defence: a role for …
2014年1月30日 · CD14 was also shown to induce Ca 2+ influx and NFAT activation causing apoptosis of differentiated DCs, but not macrophages, stimulated by LPS. NFAT2/c1 activated …
Cell cycle and apoptosis regulation by NFAT transcription ... - Nature
2016年4月21日 · In this review, we address the possible reasons for these distinct roles, particularly regarding N- and C-terminal transactivation regions (TADs) and the partner …
NFAT control of innate immunity | Blood - Blood | American …
2012年8月16日 · Numerous studies have demonstrated that LPS binding to CD14 is enhanced by LPS binding protein, which is followed by CD14-mediated transfer of LPS to the TLR4/MD2 …
Nuclear Factor of Activated T Cells 2 Transactivation in Mast Cells
The presence of the β-specific sequence is associated with both quantitative and qualitative differences in transactivation ability: NFAT2.β demonstrates a greater ability to transactivate in …
[Role of nuclear factor of activated T cells-2 in high ... - PubMed
The effect of LPS stimulation on NFAT2 and HMGB1 interaction in the cytoplasm was observed by immunoprecipitation assay. HMGB1 production and release was detected in cells with …