2024年12月25日 · NFKBIA (NFKB Inhibitor Alpha) is a Protein Coding gene. Diseases associated with NFKBIA include Ectodermal Dysplasia And Immunodeficiency 2 and Hypohidrotic …

2013年8月1日 · The NFKBIA gene provides instructions for making one piece (the alpha subunit) of the IKK protein complex, which is a group of related proteins that regulates the activity of …

2020年9月21日 · Emerging studies indicate that dysregulated NF-κB activity causes inflammation-related diseases as well as cancers, and NF-κB has been long proposed as the potential …

Our findings represent the first characterization of NFKBIA and IκBα as maternal effectors in both the bovine oocyte and embryo. We suggest a role for NFKBIA as a marker of NF-κB/p65 …

2024年12月10日 · Phosphorylated IκBα predicts poor prognosis in activated B-cell lymphoma and its inhibition with thymoquinone induces apoptosis via ROS release. Hussain AR, Uddin S, …

2025年2月20日 · HIV-1 Tat upregulates the expression of nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha (NFKBIA, IkappaB alpha) in human primary T cells …

2023年8月28日 · Transgenic mice expressing dominant-negative IkB, and exhibiting functional inhibition of NF-kB signaling in endothelial cells, were protected from age-related insulin …

Gene ID: 4792, updated on 9-Feb-2025. This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts …

The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA or NFKBIB, 604495), which inactivate NF-kappa-B by trapping it in the cytoplasm.

2011年2月26日 · Here, we focus on nuclear factor (NF)-κB, a TF involved in several cellular processes, studying NFκB - inhibitor (NFKBIA) mRNA and its protein product, IκBα, during …