Non-homologous end joining (NHEJ) is a pathway that repairs double-strand breaks in DNA. It is called "non-homologous" because the break ends are directly ligated without the need for a …

2020年4月3日 · Imprecise NHEJ mediated repair can produce insertion and/or deletion mutations of variable length at the site of the DSB. HDR-mediated repair can introduce precise point …

2023年10月8日 · 非同源末端连接（NHEJ）检测系统包含一个启动子、嘌呤抗性、GFP； 启动子通过一个puro基因与GFP编码盒分离，puro基因两侧是两个具有相同方向的I-SceI位点，当加 …

2017年5月17日 · Mammalian non-homologous DNA end joining (NHEJ) is the primary pathway for the repair of DNA double-strand breaks (DSBs) throughout the cell cycle,...

The two major pathways for repair of DNA double-strand breaks (DSBs) are homologous recombination (HR) and nonhomologous end joining (NHEJ). HR leads to accurate repair, …

DNA双链断裂修复主要通过 非同源末端连接 （Non-homologous End Joining, NHEJ）和 同源重组 （Homologous Recombination, HR）来完成，其中NHEJ容易出错并引入突变而HR具有高度的 …

2018年11月26日 · Imprecise NHEJ mediated repair can produce insertion and/or deletion mutations of variable length at the site of the DSB. HDR-mediated repair can introduce precise …

Nonhomologous DNA end-joining (NHEJ) is the predominant double-strand break (DSB) repair pathway throughout the cell cycle and accounts for nearly all DSB repair outside of the S and …

2008年9月15日 · DNA double-strand breaks (DSBs) are dangerous lesions that can lead to potentially oncogenic genomic rearrangements or cell death. The two major pathways for …

2023年6月19日 · 非同源末端连接 （Non-homolouous end joining，NHEJ） 和同源重组 （Homologous recombination，HR） 是DSB修复的两条主要通路。 一般地，HR被认为是DNA …