Near-infrared fluorescence (NIRF) is an emerging molecular intravascular imaging modality that allows for in vivo visualization of pathobiological and cellular processes at atheroma plaque level, including inflammation, oxidative stress, and abnormal endothelial permeability.

Near-infrared fluorescence (NIRF) molecular imaging holds great promise as a new “point-of-care” medical imaging modality that can potentially provide the sensitivity of nuclear medicine techniques, but without the radioactivity that can otherwise place limitations of usage.

2024年5月1日 · Expansion of the utilizable spectrum of light from the visible region to the near-infrared (NIR) window has greatly facilitated the clinical application of optical technologies for cancer imaging...

2017年1月10日 · Owing to advances in reducing photon scattering, light absorption and autofluorescence through innovations in the broad 700–1,700 nm NIR window, NIR fluorescence affords high imaging resolution...

Optical molecular imaging using near-infrared fluorescence (NIRF) light is an emerging high-resolution imaging approach to image a wide range of molecular and cellular species in vivo. Imaging using NIR wavelengths (650–900 nm) enables deeper photon penetration into tissue and reduced tissue autofluorescence, resulting in higher sensitivity ...

We developed a novel NIFCE system capable of emitting near-infrared light (NIRL) to excite NIR fluorescent dyes, which then emit NIR fluorescence (NIRF) at higher wavelengths. Simultaneously, it captures both NIRF and conventional white-light images, wirelessly transmitting them to an image receiver.

Near-infrared fluorescence (NIRF) imaging is an attractive modality for early cancer detection with high sensitivity and multi-detection capability. Due to convenient modification by conjugating with moieties of interests, NIRF probes are ideal candidates for cancer targeted imaging.

2017年4月28日 · The emergence of near infra-red fluorescence (NIRF) light for tissue scale imaging owes to the provision of highly specific images of the target organ. The special characteristics of near infra-red window such as minimal auto-fluorescence, low light scattering, and absorption of biomolecules in tissue converge to form an attractive modality for ...

2020年7月1日 · Tumor-targeted, near-infrared fluorescent (NIRF) imaging is an emerging field of real-time intraoperative cancer imaging based on tumor-targeted NIRF dyes. Targeted NIRF dyes contain NIRF fluorophores and specific binding ligands such as …

摘要: 作为术中导航的新兴领域，近红外荧光（near-infrared fluorescence，NIRF）成像技术能借助荧光探针对特定的生物组织进行显像，从而在外科手术中实时获取血管、淋巴管和特定组织的视觉信息，从而发现传统方法无法识别的微小灶，正确显示肿瘤切缘，帮助 ...