
NKX2-5 Gene - GeneCards | NKX25 Protein | NKX25 Antibody
2024年12月25日 · NKX2-5 (NK2 Homeobox 5) is a Protein Coding gene. Diseases associated with NKX2-5 include Atrial Septal Defect 7 With Or Without Atrioventricular Conduction …
Genetics of Congenital Heart Defects: The NKX2-5 Gene, a Key …
2016年1月23日 · The mutant NKX2-5 factor can regulate a number of off-targets downstream to facilitate CHD development. This review summarizes the genetic etiology of congenital heart …
Nkx2.5: a crucial regulator of cardiac development, regeneration …
Nkx2.5 is acknowledged as an early and specific indicator of cardiogenic profiles, and investigating the pathways that regulate Nkx2.5 expression will provide new insights into the …
Nkx2-5 Pathways and Congenital Heart Disease - Cell Press
2004年4月30日 · Human mutations in Nkx2-5, a cardiac homeobox gene, predominantly function in a dominant-negative fashion and cause a diverse set of congenital heart malformations that …
Genetics of Congenital Heart Defects: The NKX2-5 Gene, a Key …
NKX2-5 belongs to the NK2 family of homeobox genes and is a homolog of the tinman gene found in Drosophila melanogaster. It functions as a key regulator in cardiac morphogenesis, …
Nkx2-5 defines a subpopulation of pacemaker cells and is
2019年7月25日 · Nkx2-5 is a key transcription factor essential for the formation of the working myocardium, but it was generally thought to be detrimental to SAN development. However, …
NKX2-5 regulates human cardiomyogenesis via a HEY2 …
2018年4月10日 · Here, we show deletion of NKX2-5, a critical component of the cardiac gene regulatory network, in human embryonic stem cells (hESCs), results in impaired …
NKX2-5 NK2 homeobox 5 [ (human)] - National Center for …
NKX2-5 is genetically associated with scleroderma, pulmonary hypertension, and fibrosis. Functional evidence revealed a regulatory mechanism that results in NKX2-5 transcriptional …
NKX2-5 NK2 homeobox 5 [ Homo sapiens (human) ] - National …
2025年2月8日 · NKX2-5: an update on this hypermutable homeodomain protein and its role in human congenital heart disease (CHD). Reamon-Buettner SM, et al. Hum Mutat, 2010 Nov. …
NKX2-5 NK2 homeobox 5 - NIH Genetic Testing Registry (GTR)
2024年9月18日 · Mutations in this gene cause atrial septal defect with atrioventricular conduction defect, and also tetralogy of Fallot, which are both heart malformation diseases. Mutations in …
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