NMD3 Gene - GeneCards | NMD3 Protein | NMD3 Antibody
2024年12月25日 · NMD3 (NMD3 Ribosome Export Adaptor) is a Protein Coding gene. Diseases associated with NMD3 include Palmoplantar Keratoderma, Bothnian Type and Shwachman …
NMD3 - Wikipedia
60S ribosomal export protein NMD3 is a protein that in humans is encoded by the NMD3 gene. [5] [6] [7]
Structural snapshots of human pre-60S ribosomal particles
2020年7月15日 · Here we present four structures of human pre-60S particles isolated through a nuclear export factor NMD3, representing assembly stages immediately before and after …
Nature︱美国加利福尼亚州斯克里普斯研究所团队由海洋中环状亚 …
研究者利用化学蛋白质组学阐明了PA的细胞靶点，揭示PA能够靶向核糖体60S亚基输出蛋白 NMD3，阻断多聚体形成并抑制蛋白质翻译，发挥强大的抗肿瘤作用。 受萜类化合物的两相合 …
NMD3 核糖体输出适配器（NMD3）基因 | MCE - MCE-生物活性 ...
nmd3 核糖体输出适配器： 核糖体 40s 和 60s 亚基结合在核仁中并输出到细胞质。 该基因编码的蛋白质参与 60S 亚基通过核孔复合体进入细胞质的过程。 该基因存在多个转录本变体，但迄 …
Synthesis of portimines reveals the basis of their anti-cancer …
2023年9月20日 · NMD3 is an adaptor of 60S ribosomal subunit nuclear export and is released after pre-60S maturation and subsequent polysome formation, though the precise mechanism …
Structural snapshot of cytoplasmic pre-60S ribosomal particles
2017年1月23日 · Nmd3, a highly conserved protein in eukaryotes, is a specific adaptor required for the export of pre-60S particles. Here we used cryo-electron microscopy (cryo-EM) to …
NMD3 NMD3 ribosome export adaptor [ (human)] - National …
2025年2月8日 · Gene ID: 51068, updated on 8-Feb-2025. Ribosomal 40S and 60S subunits associate in the nucleolus and are exported to the cytoplasm. The protein encoded by this …
NMD3 Encodes an Essential Cytoplasmic Protein Required for …
A mutation in NMD3 was found to be lethal in the absence of XRN1, which encodes the major cytoplasmic exoribonuclease responsible for mRNA turnover. Molecular genetic analysis of …
Baran等组Nature：Portimines的高效全合成和抗癌活性机制
2023年10月23日 · 化学蛋白质组学实验进一步确定 portinine A的主要靶点是60S核糖体输出蛋白NMD3。 几十年以来，环亚胺毒素引起了科学界的广泛兴趣，其具有独特的化学结构和强效生 …