The NPAS4 gene is a neuronal activity-dependent immediate early gene that has been identified as a transcription factor. The protein regulates the transcription of genes that control inhibitory …

2024年12月25日 · NPAS4 (Neuronal PAS Domain Protein 4) is a Protein Coding gene. Diseases associated with NPAS4 include Autism Spectrum Disorder and Inflammatory Bowel Disease …

2023年2月15日 · By characterizing the landscape of activity-induced DNA double-strand breaks in the brain, we show that NPAS4–NuA4 binds to recurrently damaged regulatory elements and …

这种经历与神经元PAS结构域蛋白4（Npas4）的表达有关，Npas4是一种公认的其他神经元基因的调节剂。 在这期的1282页，秋木等报告了Npas4表达式的分子细节是如何受控的，它包括编 …

Neuronal PAS domain protein 4 (Npas4) is a recently discovered calcium-dependent transcription factor that regulates the activation of genes involved in the homeostatic regulation of …

2021年10月20日 · Our data indicate that NPAS4 is necessary for normal transcriptional responses to light in the SCN and critical for photic phase-shifting of circadian behavior. …

2014年5月22日 · Npas4 is an early-response transcription factor that is enriched in the brain and induced in excitatory neurons specifically upon calcium influx and that has been suggested to …

2013年11月6日 · The transcription factor NPAS4 enables neurons to distinguish synaptic inputs received at their soma or dendrites; sensory stimulation increases NPAS4 which promotes...

2021年10月20日 · Our data indicate that NPAS4 is necessary for normal transcriptional responses to light in the SCN and critical for photic phase-shifting of circadian behavior.

2016年3月14日 · Npas4 is involved in activity-dependent synaptic modulation in both excitatory and inhibitory neurons. It regulates the expression of a large number of activity-regulated …