
NPC2 Gene - GeneCards | NPC2 Protein | NPC2 Antibody
2024年12月25日 · NPC2 (NPC Intracellular Cholesterol Transporter 2) is a Protein Coding gene. Diseases associated with NPC2 include Niemann-Pick Disease, Type C2 and Niemann-Pick …
Epididymal secretory protein E1 - Wikipedia
The epididymal secretory protein E1, also known as NPC2 (Niemann-Pick intracellular cholesterol transporter 2), is one of two main lysosomal transport proteins that assist in the regulation of …
【科技前沿】颜宁/杨洪远合作团队解析胆固醇进入细胞的分子机制
2020年6月15日,普林斯顿大学颜宁教授与新南威尔士大学杨洪远教授合作在Cell杂志上发表了题为Structural Basis of Low-pH-Dependent Lysosomal Cholesterol Egress by NPC1 and NPC2 …
胆固醇分子“一波三折”的“转运旅程” - 中国科学院
2020年6月16日 · NPC2是一个可溶蛋白,而NPC1是一个膜蛋白。它由13个跨膜螺旋和3个位于腔内侧的可溶结构域(即NTD、domain C、domain I)组成。其中,第3~7个跨膜螺旋构成了一 …
The characteristics and biological significance of NPC2
2019年10月1日 · Niemann–Pick C disease (NPC) is a rare autosomal recessive disorder characterized by severe neurodegeneration of central nervous system. Linkage studies in …
Cell | 颜宁/杨洪远合作团队解析胆固醇进入细胞的分子机制
2020年6月15日,普林斯顿大学 颜宁 教授与新南威尔士大学 杨洪远 教授合作在 Cell 杂志上发表了题为 Structural Basis of Low-pH-Dependent Lysosomal Cholesterol Egress by NPC1 and …
NPC2 NPC intracellular cholesterol transporter 2 [ (human)]
2025年2月8日 · Recombinant NPC2 protein increases triglyceride levels in body fat. these results suggest that the vitamin A-mediated antimicrobial mechanism against M. tuberculosis requires …
NPC2 gene - MedlinePlus
The NPC2 gene provides instructions for making a protein that is located inside lysosomes, which are compartments in the cell that digest and recycle materials. Learn about this gene and …
NPC 细胞内胆固醇转运蛋白 2(NPC2)基因 | MCE
该基因编码一种含有脂质识别结构域的蛋白质。 编码的蛋白质可能通过晚期内体/溶酶体系统调节胆固醇的转运。 该基因的突变与尼曼匹克病、C2 型和额叶萎缩有关。 [RefSeq 提供,2008 …
The characteristics and biological significance of NPC2 ... - PubMed
Niemann-Pick C disease (NPC) is a rare autosomal recessive disorder characterized by severe neurodegeneration of central nervous system. Linkage studies in multiplex NPC families and …