002105 NZO/HlLtJ NZO inbred mice and strains derived from them develop severe obesity, and are thus useful for studying obesity and Type 2 diabetes.

2002年7月1日 · New Zealand Obese (NZO)/HlLt male mice exhibit a polygenic obesity and approximately 50% develop type 2 diabetes. This strain is known to produce a variety of …

In this context, we investigated whether New Zealand obese (NZO/HlLtJ) mice, which have anatomic and functional characteristics similar to those of obese patients with OSAS, suffer …

Here, we show that New Zealand obese (NZO) mice display similar metabolic characteristics such as obesity, leptin insensitivity, glucose intolerance, and IR. Importantly, NZO mice are poor …

1979年5月24日 · THE New Zealand obese (NZO) mouse is characterised by obesity, hyperinsulinaemia, insulin resistance and mild glucose intolerance 1–8. It has been thought of …

Carbohydrate-free diet prevents hyperglycaemia and beta cell destruction in the New Zealand Obese (NZO) mouse model. Here we have used a sequential dietary regimen to dissociate the …

2020年5月6日 · Here, we compared the metabolic changes in pregnant normal NMRI mice with those in New Zealand obese (NZO) mice. Male animals of this strain are an established model …

These data suggest that MR induces FGF21 and protects NZO mice from high-fat diet-induced glucose intolerance and type 2 diabetes. The normoglycemic phenotype in vegans and …

The New Zealand Obese (NZO) mouse was studied as a potential model for autoimmune diabetes. NZO mice develop obesity, glucose intolerance, and insulin resistance, and have low …

2004年7月1日 · 大约50%的NZO/HlLt男性发展为慢性胰岛素抵抗型2型糖尿病综合征，并伴有2个不寻常的特征:富含B淋巴细胞的岛周浸润和抗胰岛素受体自身抗体(AIRAs)的发展。