Although amines are good nucleophiles, we cannot use them is a direct SN 2 reaction to achieve the OH to NH 2 conversion because the hydroxide ion is a poor leaving group. So, the strategy …

2013年1月17日 · For PhOH to PhNH2 Pd catalysis offers a better route than Zn reduction etc. Formation of the triflate by reaction with triflic anhydride then reaction under Pd catalysis with …

2023年1月23日 · A clear step toward improving the reactivity of alcohols in S N 2 reactions would be to modify the –OH functional group in a way that improves its stability as a leaving anion. …

Halides are less reactive than sulfonate esters, however elimination as a competing side reaction is also reduced. - sulfonate esters can be converted to halides with the sodium halide in …

一步变成氨基只能是-oh——→-nh2，没什么好说的了。不过，α-羟基腈加氨就成了α-氨基腈，应该算是符合楼主的要求吧。

The Mitsunobu Reaction allows the conversion of primary and secondary alcohols to esters, phenyl ethers, thioethers and various other compounds. The nucleophile employed should be …

Use a molar ratio of NH2/NCO ~ 0.5 to react only one of the NCOs. Use a solvent such as acetone or n-pyrrol at less than 60oC. The reaction of amines with isocyanate is fast and easy.

虽然O-H和N-H的区域重叠，但N-H吸收通常有一个或两个尖锐的低强度的吸收频带，而O-H在N-H的区域时，通常是一个宽的吸收峰，此外伯胺在这一区域有两个吸收峰。 胺基N-H与羟基O …

Amines from Alcohols Via Substitution Reactions Although amines are good nucleophiles, we cannot use them is a direct SN2 reaction to achieve the OH to NH2 conversion because the …

吸电子吧，这些基团的是连在c上的，且电负性比c大，因此会从c上吸电子。-oh,-och3等基团连接在共轭体系中才可能表现为供电子。