What is oral immunotherapy for food allergy? Oral immunotherapy (OIT) refers to feeding an allergic individual an increasing amount of an allergen with the goal of increasing the threshold that triggers a reaction. For example, a person allergic to peanuts may be given very small amounts of peanut protein that would not trigger a reaction.

Oral immunotherapy (OIT) is now recognized as an alternative active treatment to strict food avoidance in certain patients with IgE-mediated food allergy. Studies have confirmed the efficacy of OIT to desensitize children with allergy to cow's milk, eggs, and peanuts.

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A food allergy patient taking oral immunotherapy (OIT) ingests increasing doses of their allergen to desensitize their immune system, training their immune system to not react to the problem food. OIT has a long history – one early account of using OIT to …

2024年12月17日 · Food-allergic individuals currently have 2 Food and Drug Administration– approved therapeutic options available to them aside from life-long allergen avoidance: oral immunotherapy (OIT) and omalizumab. OIT for food allergy has been extensively studied in clinical trials and currently provides the greatest level of protection; however, it also ...

The initial purpose of OIT is to protect patients from anaphylaxis due to accidental exposure to trace amounts of the causative food allergen. However, OIT still needs to be clinically practiced due to significant safety concerns and uncertainties regarding whether tolerance will be achieved despite prolonged therapy. 25 A complete cure may not ...

2025年2月12日 · Food oral immunotherapy (OIT) is an option for the treatment of immunoglobin E (IgE)‐mediated food allergy that involves administering gradually increasing doses of an allergenic food over time (under medical supervision) with the …

2025年2月12日 · Food oral immunotherapy (OIT) is an option for the treatment of immunoglobin E (IgE)-mediated food allergy that involves administering gradually increasing doses of an allergenic food over time (under medical supervision) with the …

2025年3月6日 · OIT, the standard food allergy treatment in the U.S., involves gradually increasing exposure to an allergen to build tolerance. By the end of the study, 36% of participants who received an extended course of omalizumab could tolerate at least 2 grams of peanut protein—equivalent to about eight peanuts—along with two other allergens. In ...

2020年3月18日 · Oral immunotherapy (OIT) consists of daily ingestion of the offending food allergen (food dosing), starting below a patient’s threshold dose (i.e. the minimum amount that would elicit a reaction), and increasing the dose over time with a goal of increasing clinical tolerance to that food.