OAS2 Gene - GeneCards | OAS2 Protein | OAS2 Antibody
2024年12月25日 · OAS2 (2'-5'-Oligoadenylate Synthetase 2) is a Protein Coding gene. Diseases associated with OAS2 include Microphthalmia With Limb Anomalies and Tick-Borne …
OAS2 - Wikipedia
2'-5'-oligoadenylate synthetase 2 is an enzyme that in humans is encoded by the OAS2 gene. [5] [6] This gene encodes a member of the 2-5A synthetase family, essential proteins involved in …
文献分享 | Immunity：OAS通过2-5A的细胞间转移，在细胞间交叉 …
接下来，我们研究了2-5a是否可以从哺乳动物细胞中输出。我们首先比较了人类和小鼠细胞中oas1、oas2和oas3的蛋白丰度，这表明它们的酶促能力产生2-5a（图s3a-s3c）。所有细胞在 …
Oligoadenylate synthase-like (OASL) proteins: dual functions …
2015年3月6日 · One of the key antiviral factors induced by IFNs, 2′-5′ oligoadenylate synthase (OAS), is a well-known molecule that regulates the early phase of viral infection by degrading …
Epigenetic regulation of OAS2 shows disease-specific DNA
2016年8月30日 · Exploring mechanisms of epigenetic changes in OAS2 will be useful for illustrating the role of OAS2 in human diseases. In a broader context, our data provide novel …
南京大学吴稚伟课题组报道了叶酸代谢调控抗病毒天然免疫的机制
2023年3月16日 · 2’-5’寡聚腺苷酸合成酶（2’-5’ oligoadenylate synthetase , OAS）是一类广谱抗病毒蛋白，包括4个成员：OAS1-3和OASL，是抗病毒天然免疫中的关键效应因子。 OAS能够识 …
OAS proteins and cGAS: unifying concepts in sensing and
2014年7月18日 · Upon double-stranded RNA (dsRNA) binding, oligoadenylate synthase (OAS) enzymes undergo a conformational switch, which results in their catalytic activity — that is, the …
2'-5'-寡聚腺苷酸合成酶 2（OAS2）基因 | MCE
该基因编码 2-5A 合成酶家族的成员，这是参与对病毒感染的先天免疫反应的必需蛋白质。 编码的蛋白质由干扰素诱导，并在 2'-特异性核苷酸转移反应中使用三磷酸腺苷合成 2',5'-寡聚腺苷酸 …
OAS1, OAS2 and OAS3 restrict intracellular - ScienceDirect
OAS1, OAS2 and OAS3 enhance pro-inflammatory cytokine secretion but have no effect on the secretion of the anti-inflammatory cytokine IL-10. The OASs therefore enhance anti …
OAS2 2'-5'-oligoadenylate synthetase 2 [ Homo sapiens …
2024年12月10日 · Title: Epigenetic regulation of OAS2 shows disease-specific DNA methylation profiles at individual CpG sites. we characterized the functional consequences of the …