The WHO ordinal severity scale has been used to predict mortality and guide trials in COVID-19. However, it has its limitations. The present study aims to compare three classificatory and predictive models: the WHO ordinal severity scale, the model ...

Objective: The present study aims to compare three classificatory and predictive models: the WHO ordinal severity scale, the model based on inflammation grades, and the hybrid model. Design: Retrospective cohort study with patient data collected and followed up from March 1, 2020, to May 1, 2021, from the nationwide SEMI-COVID-19 Registry.

The World Health Organization (WHO) Ordinal Scale (OS) has been used to measure clinical improvement among clinical trial participants and has the benefit of measuring effect across the spectrum of clinical illness. We modified the WHO OS to enable assessment of COVID-19 patient outcomes using electronic health record (EHR) data. Methods

2022年7月9日 · The objective of this study is to develop a scalable, time-sensitive ordinal scale (OS) to facilitate robust, clinically relevant evaluation of COVID-19 disease progression and patient outcomes evaluation for use in multi-site, real-world studies using EHR data.

2020年6月12日 · This set includes three elements: a measure of viral burden (quantitative PCR or cycle threshold), a measure of patient survival (mortality at hospital discharge or at 60 days), and a measure of patient progression through the health-care system by use of the WHO Clinical Progression Scale, which reflects patient trajectory and resource use over...

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2020年10月1日 · In many ongoing and planned clinical trials, the efficacy of treatments of patients with the COVID-19 disease caused by SARS-CoV-2 is being measured by an ordinal scale whose categories represent severity of illness over time via the degree of medical intervention applied, with higher scores for interventions that are more burdensome for the ...

2022年7月9日 · Modifying the existing WHO Clinical Progression Scale, we developed an ordinal severity scale (OS) and assessed its usefulness in the analyses of COVID-19 patient outcomes using retrospective EHR data.

OBJECTIVE: The present study aims to compare three classificatory and predictive models: the WHO ordinal severity scale, the model based on inflammation grades, and the hybrid model. DESIGN: Retrospective cohort study with patient data col-lected and followed up from March 1, 2020, to May 1, 2021, from the nationwide SEMI-COVID-19 Registry.

2023年3月1日 · This trial was originally designed to compare clinical status at day 15 using an eight-category ordinal scale. Scores on the ordinal scale are as follows: 1, not hospitalized, no limitations of activities; 2, not hospitalized, limitation of activities, home oxygen requirement, or both; 3, hospitalized, not requiring supplemental oxygen and no ...