OSW-1 | ORP4拮抗剂 | MCE - MCE-生物活性分子大师
OSW-1, isolated from Ornithogalum caudatum, is a specific antagonist of osterol-binding protein (OSBP) and OSBP-related protein 4 (ORP4) with GI50s in the nanomolar range in human …
Anticancer Effects and Mechanisms of OSW-1 Isolated From
2021年9月23日 · In this regards, OSW-1, which was isolated from the bulbs of Ornithogalum saundersiae in 1992, has exhibited powerful anticancer activities in various cancers. However, …
OSW-1: a natural compound with potent anticancer activity and
2005年12月7日 · Using various human cancer and nonmalignant cell lines, we investigated the anticancer activity and selectivity of OSW-1 and its underlying mechanisms of action. OSW-1 …
Anticancer Effects and Mechanisms of OSW-1 Isolated From
2021年9月22日 · In 1992, Kubo S et al. (9) isolated OSW-1, a steroidal saponins, from the bulbs of O. saundersiae, which has a high cytotoxicity to cancer cells. Its anticancer effect is about …
Anticancer saponin OSW-1 is a novel class of selective Golgi stress ...
2019年7月15日 · OSW-1 is a plant-derived natural product proposed to selectively kill cancer cells by binding to members of the oxysterol binding protein family, thereby disrupting lipid/sterol …
OSW-1通过调节PI3K/AKT信号通路对胶质瘤细胞的抗癌作用：一种 …
OSW-1 分离自 Ornithogalum saundersiae，对各种恶性癌细胞具有抗癌活性。 然而，OSW-1 对胶质瘤的影响及其潜在机制仍不清楚。 方法： 网络药理学用于预测 OSW-1 对胶质瘤的抗癌作 …
虎眼万年青皂苷OSW-1构效关系研究进展 - 百度学术
OSW-1是20世纪90年代日本科学家从虎眼万年青 (Ornithogalum saundersiae)球茎中分离得到的一种甾体皂苷类物质,结构见图1. 百度学术集成海量学术资源，融合人工智能、深度学习、大数 …
OSW-1: a Natural Compound With Potent Anticancer ... - Oxford …
2005年12月7日 · Using various human cancer and nonmalignant cell lines, we investigated the anticancer activity and selectivity of OSW-1 and its underlying mechanisms of action. OSW-1 …
OSW-1 - 百度百科
这一惊人发现，使OSW-1成为21世纪国际医学界抗癌研究领域的最强新秀，与此同时目前我国唯一含有“OSW-1”的抗癌新药——“复方万年青胶囊”，正式被国家食品药品监督管理局（FSDA） …
OSW-1 (CAS 145075-81-6) - Cayman Chem
OSW-1 is a saponin that has been found in O. saundersiae and has antiviral and anticancer activities. 1 It is an inhibitor of oxysterol-binding protein (OSBP) and its paralog OSBP-related …