
sc-OTGM: Single-Cell Perturbation Modeling by Solving Optimal …
May 6, 2024 · The core function of sc-OTGM is to create a probabilistic latent space utilizing a GMM as its prior distribution and distinguish between distinct cell populations by learning their …
使用神经最优传输学习单细胞扰动响应 - 知乎 - 知乎专栏
本文的研究基于生物学的数学基础,利用 最优输运理论 建立了一个新的框架,称为 CellOT,用于学习单细胞在扰动下的演化轨迹。 通过学习最优输运映射,CellOT能够预测细胞在扰动下的 …
sc-OTGM: Single-Cell Perturbation Modeling by Solving Optimal …
This is the official codebase for "sc-OTGM: Single-Cell Perturbation Modeling by Solving Optimal Mass Transport on the Manifold of Gaussian Mixtures" - Novartis/scOTGM
we present sc-OTGM, streamlined with less than 500K parameters, making it ap-proximately 100x more compact than the foundation models, offering an efficient alternative. sc-OTGM is an …
sc-OTGM: Single-Cell Perturbation Modeling by Solving Optimal …
The core function of sc-OTGM is to create a probabilistic latent space utilizing a Gaussian mixture model (GMM) as its prior distribution and distinguish between distinct cell populations by …
STU-BioMLGroup/OTGM - GitHub
Contribute to STU-BioMLGroup/OTGM development by creating an account on GitHub.
sc-OTGM: Single-Cell Perturbation Modeling by Solving Optimal …
May 6, 2024 · We evaluated our model against a CRISPR-mediated perturbation dataset, called CROP-seq, consisting of 57 one-gene perturbations. Our results demonstrate that sc-OTGM is …
sc-OTGM:通过在高斯混合物流形上解决最优质量传输的单细胞扰 …
通过使用单细胞基因组学数据,我们提出了一种名为sc-OTGM的简化模型,它通过无监督学习实现了细胞状态分类和基因干扰响应预测,并且在分析差异基因表达,基因推荐系统以及生成特定 …
OTGM: Graph Matching with Noisy Correspondence via Optimal …
Sep 17, 2024 · Graph matching is a significant task for handling the matching problem of finding correspondences between keypoints in different graphs. Prior research primarily concentrates …
OTGM - What does OTGM stand for? The Free Dictionary
Looking for online definition of OTGM or what OTGM stands for? OTGM is listed in the World's most authoritative dictionary of abbreviations and acronyms