Phospho-eIF2α (Ser51) Antibody | Cell Signaling Technology
Polyclonal Antibody for studying EIF2S1/eIF2-alpha (Ser52) phosphate. Validated for WB, WB. Available in 2 sizes. Highly specific and rigorously validated in-house, Phospho-eIF2α (Ser51) …
真核起始因子2 - 维基百科，自由的百科全书
eIF2 （eukaryotic Initiation Factor 2，真核起始因子2）是一个重要的 真核起始因子，它的作用是在 真核翻译 起始过程中介导起始 tRNA （Met-tRNA i）与 核糖体 结合。 它是一个异源三聚 …
Phosphorylation of eukaryotic initiation factor-2α (eIF2α) in …
2020年6月8日 · EIF2AK2, commonly known as protein kinase R (PKR), is activated by viruses and alcohol 11, 12. EIF2AK3, commonly known as protein kinase R-like endoplasmic …
Phospho-eIF2α (Ser51) (D9G8) XP - Cell Signaling Technology …
Monoclonal Antibody for studying EIF2S1/eIF2-alpha (Ser52) phosphate. Validated for IHC, IP, WB. Available in 2 sizes. Highly specific and rigorously validated in-house, Phospho-eIF2α …
eIF2 调控 | Cell Signaling Technology
eIF2 起始复合体整合了各种各样应激相关的信号来调控全局和特异性 mRNA 翻译。 在适宜的条件下，eIF2 会结合 GTP 和 Met-tRNAi 形成三元复合体 (TC)，三元复合体随后结合 40S 核糖体 …
Phosphorylation of the translation initiation factor eIF2
2015年1月15日 · At the molecular level, we demonstrate that eIF2 α P acts through an ATF4-independent mechanism to control Akt activity via the regulation of mTORC1. Specifically, …
Modulation of p-eIF2α cellular levels and stress granule assembly ...
2017年3月9日 · We found that pretreatment of cells with a natural disaccharide trehalose, a known autophagy enhancer, delays SG assembly and facilitates their premature post-stress …
碧云天生物技术-Phospho-eIF-2α (Ser51) Rabbit Polyclonal Antibody (p …
Phosphorylation of the eukaryotic initiation factor 2 (eIF2) α subunit is a well-documented mechanism to downregulate protein synthesis under a variety of stress conditions. eIF2 binds …
eIF2α信号通路相关研究进展 - 百度文库
目前发现了四种磷酸化eIF2α的丝氨酸琳氨酸蛋白激酶，分别是HRI，PERK，PKR及GCN2。 本文就该信号通路的研究进展进行总结分析。 eIF2α的磷酸化现象最早在兔网织红细胞中发现：血 …
The integrated stress response in neurodegenerative diseases
2025年2月19日 · Once activated, PERK then phosphorylates eIF2α (p-eIF2α), preventing the translation of mRNA and reducing protein synthesis, which allows the ER to either refold or …