
Peptide Antibody Reactivity to Homologous Regions in Glutamate ...
2022年4月17日 · In the current study, we aimed to analyze whether antibody cross-reactivity between CVB4 P2C and GAD may contribute to the onset of T1D and/or SPS. In total, 12 …
Comparison of Nucleotide Sequence of P2C Region in
2004年11月1日 · A sequence of six identical amino acids (PEVKEK) is shared by the 2C protein of Coxsackie virus B and the glutamic acid decarboxylase (GAD) molecules. Between 1995 …
Analysis of antibody responses against coxsackie virus B4 protein …
The sequence homology between the coxsackie B4 virus nonstructural protein 2C (CVB4 p2C) and the major diabetes autoantigen glutamic acid decarboxylase (GAD(65)) provides a basis …
神经综述:谷氨酸脱羧酶(GAD)抗体与神经系统疾病
2021年4月30日 · 对小鼠脑组织切片进行免疫组织化学染色或cba法检测,gad免疫反应阳性提示gad抗体滴度≥1800u/ml(放射免疫分析法定量测定),以线点技术检测,gad免疫反应阳性提 …
icry between protein 2C (p2C) of coxsackie virus B4 and the autoantigen glutamic acid decarboxylase (GAD65) plays a role in the pathogenesis of insulin-dependent diabetes …
(PDF) Comparison of Nucleotide Sequence of P2C Region in
2004年12月1日 · Our data showed that the viral p2C sequence with homology with GAD is highly conserved in CVB5 isolates. There was no difference between diabetogenic and non …
Molecular mimicry in diabetes mellitus: the homologous domain in ...
It has been proposed that molecular mimicry between protein 2C (p2C) of coxsackie virus B4 and the autoantigen glutamic acid decarboxylase (GAD65) plays a role in the pathogenesis of …
Immunological characterization of antibodies against synthetic …
1996年7月15日 · Our study highlights the usefulness of peptides as diagnostic antigens in T1DM and LADA, and extends previous findings by comparing IgM and IgG-isotype antibodies in the …
Peptide Antibody Reactivity to Homologous Regions in Glutamate ...
In the current study, we aimed to analyze whether antibody cross-reactivity between CVB4 P2C and GAD may contribute to the onset of T1D and/or SPS. In total, 12 mice were immunized …
Molecular mimicry in diabetes mellitus: the homologous domain in ...
In this study we show that the amino acid sequence of p2C which shares homology with a sequence in GAD65 (PEVKEK), is highly conserved in coxsackie virus B4 isolates as well as …
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