2005年9月1日 · In this review, we present and discuss recent knowledge about p40 phox, the last NADPH oxidase component to be identified. Furthermore, its interaction with cellular pathways …

PX 结构域见于超过 250 个种蛋白，包括 NADPH 氧化酶复合体的 p40 phox 和 p47 phox 组分、分选连接蛋白、磷脂酶 D1 和 2 以及激酶 PI3K 和 CISK。 PX 结构域包括一个氨基末端三链 β …

2001年6月12日 · PX domains, named for their presence in the p40phox and p47phox subunits of the NADPH oxidase 1, are ∼ 140-amino-acid-long modules found in more than 150 eukaryotic …

In this review, we present and discuss recent knowledge about p40phox, the last NADPH oxidase component to be identified. Furthermore, its interaction with cellular pathways outside of the …

2023年6月23日 · P40 phox has a special function in this process: it directs the NOX2 complex to the membranes of phagosomes, the vacuoles that contain ingested microorganisms, thus …

We show here that a novel component, p40phox, forms an activation complex with p47phox and p67phox with which it translocates to the membrane to associate with the flavocytochrome b. …

Biallelic loss-of-function (LOF) mutations of the NCF4 gene, encoding the p40 phox subunit of the phagocyte NADPH oxidase, have been described in only 1 patient. We report on 24 p40 phox …

Here we have explored the interaction between the actin cytoskeleton and p40 phox, one of the cytosolic components of NADPH oxidase. Full length p40 phox expressed in COS cells co …

2005年9月1日 · In this review, we present and discuss recent knowledge about p40phox, the last NADPH oxidase component to be identified. Furthermore, its interaction with cellular pathways …

Here we show that the PtdIns (3)P-binding activity of p40 phox is normally inhibited by the PB1 domain both in vivo and in vitro. The crystal structure of the full-length p40 phox reveals that …