2022年10月26日 · 甲型流感病毒(iav)聚合酶蛋白pb2已显示通过阻断干扰素(ifn)的诱导来部分抑制宿主免疫反应。 然而，调节IFNs下游信号通路的IAV PB2蛋白没有很好的表征。

2022年10月21日 · Influenza A virus (IAV) polymerase protein PB2 has been shown to partially inhibit the host immune response by blocking the induction of interferons (IFNs). However, the …

We recently developed a replication-incompetent PB2-knockout (PB2-KO) influenza virus that possesses a reporter gene (the green fluorescent protein gene) in the coding region of the …

In the current study, we generated PB2-KO virus expressing PspA as a bivalent vaccine for influenza and pneumococcal pneumonia and examined whether intranasal immunization with …

Be Creative - Versatile & easy to use! Bake. Blend. Mix. PB2 can be reconstituted with any liquid of choice - water, juice, etc, to make smoothies or shakes, eaten as a powder, or used in …

2019年1月11日 · 在这项研究中，我们的目标是评估基于 PB2 和 NS 基因片段的两种新的 RT-PCR 检测方法。 季节性流感病毒估计每年导致 0.3-0.6 百万人死亡。 禽流感病毒H5N1、H7N9 …

2017年4月4日 · Virus-specific IgG and IgA antibodies were detected in mice immunized with the viruses, and the immunized mice showed milder clinical signs and/or lower virus replication …

In addition, these PB2-KO viruses efficiently elicited virus-specific IgA responses, which are associated with protection from virus challenge (24–27). However, the neutralizing antibody …

文章对PB2蛋白的结构和功能特征及其在哺乳动物适应性机制方面的最新 研究进展进行归纳总结，为揭示流感病毒跨物种传播机制及相关防控手段的完善提供参考信息。 关键词: 流感病 …

2020年12月22日 · Conversely, tear IgA antibody levels were significantly higher in the PB2-D309N and PC4 groups than in the mock and IIV groups (Fig. 10B). Collectively, these data …