2022年2月15日 · The parabrachial nucleus (PBN) and thalamic paraventricular nucleus (PVT) are critical for modulating affective states in mice. However, the functional roles of PBN-PVT …

2023年5月3日 · The present study identified that the PBN-central medial thalamic nucleus (CM)-medial prefrontal cortex (mPFC) pathway is essential for itch signal transmission at the …

2023年8月4日 · Potentiation of excitatory synaptic transmission in the parabrachial nucleus (PBN) to central amygdala (CeA) pathway has been reported in rodent models of persistent pain.

Within the key nociception relay center parabrachial nucleus (PBN), we demonstrated that neurons projecting to the lateral hypothalamus (LH PBN) are nociceptive yet distinct from …

Cartoon sagittal section of mouse brain showing the approximate locations of CGRP neurons in the parabrachial nucleus (PBN), their inputs from the spinal cord and the nucleus tractus …

We report a method to record from PBN neurons of behaving, head-restrained mice, while applying reproducible noxious stimuli. We find that both spontaneous and evoked activity are …

2022年11月1日 · The Calca Cre mice were used to identify mRNAs that were selectively being translated in neurons that express the Calca gene by injecting a virus expressing a Cre …

2023年8月2日 · We report a method to record from PBN neurons of behaving, head-restrained mice while applying reproducible noxious stimuli. We find that both spontaneous and evoked …

2024年1月26日 · Mice were injected with AAV-DIO-GCaMP6s virus into the LPBN and optical fibers were implanted over the LPBN to monitor the cellular activity of LPBN neurons in awake …

2022年1月1日 · In this study, a chronic neuropathic pain (CNP) model was established using partial sciatic nerve ligation (PSNL) in mice to observe the effects of direct suppression of the …