2024年12月25日 · PCDH15 (Protocadherin Related 15) is a Protein Coding gene. Diseases associated with PCDH15 include Usher Syndrome, Type If and Deafness, Autosomal …

Family members encode integral membrane proteins that mediate calcium -dependent cell-cell adhesion. The protein product of this gene consists of a signal peptide, 11 extracellular …

2022年5月30日 · Herein, we show that Pcdh15 knockdown significantly increases extracellular signal-related kinase (ERK) phosphorylation and activation to enhance OPC proliferation in …

2025年2月8日 · Protocadherin 15 suppresses oligodendrocyte progenitor cell proliferation and promotes motility through distinct signalling pathways. Whole-exome sequencing for ocular …

2023年4月26日 · Usher syndrome type 1 F (USH1F), caused by mutations in the protocadherin-15 gene (PCDH15), is characterized by congenital deafness, lack of balance, and progressive …

Family members encode integral membrane proteins that mediate calcium-dependent cell-cell adhesion. It plays an essential role in maintenance of normal retinal and cochlear function. …

2024年5月28日 · Recent extensive genomic studies have implicated the protocadherin-related 15 (PCDH15) gene in the onset of psychiatric disorders, such as bipolar disorder (BD). To further …

The mouse Ames waltzer hearing-loss mutant is caused by mutation of Pcdh15, a novel protocadherin gene. Nature Genet. 27: 99-102, 2001.

2024年12月10日 · Family members encode integral membrane proteins that mediate calcium-dependent cell-cell adhesion. It plays an essential role in maintenance of normal retinal and …

这个基因是钙粘蛋白超家族的成员之一。 家族成员编码整合膜蛋白，调节钙依赖的细胞间粘附。 它在维持正常的视网膜和耳蜗功能中扮演着关键角色。 这个基因的突变导致听力损失和Usher …