2016年10月11日 · The PCI is calculated by adding the scores of all 13 regions together with a maximum score of 39 (13×3). In colorectal cancer, the PCI is closely correlated with the prognosis after HIPEC. The higher the PCI, the worse the prognosis. Most institutes have …

2021年6月18日 · HIPEC, often combined with surgical cytoreduction, is a heavy procedure with a non-negligible morbidity and mortality rate even in the most efficient centers; it must be performed in university centers specializing in oncological surgery with multimodal and multidisciplinary care.

2021年3月3日 · The PCI is determined during laparotomy by 2 experienced surgeons and plays a major role in the decision to proceed with CRS-HIPEC. The primary objective of this study was to determine the accuracy of the surgical PCI (sPCI) by comparing it with the PCI confirmed by the pathologist (pPCI).

Objective: The role of cytoreductive surgery (CRS) plus hyperthermic intraperitoneal chemotherapy (HIPEC) in gastric cancer with peritoneal metastasis (GCPM) is still controversial, mainly due to the limited survival benefit and uncertain patient selection. This study aims to construct a selecting strategy in GCPM for CRS + HIPEC.

Combining cytoreductive surgery (CRS) with Hyperthermic IntraPeritoneal Chemotherapy (HIPEC) can benefit patients with peritoneal metastasis from colorectal cancer. The present study evaluates the small bowel subset of the Peritoneal Cancer Index (Small-Bowel-PCI score (SB-PCI), min-max 0–12) as a prognostic factor in such patients.

基于PERISCOPE I的结果，荷兰作者开发了PERISCOPE II试验（NCT03348150）研究与姑息性SC相比，新辅助SC后胃切除术和CRS联合HIPEC在特定GC和PM患者中是否具有生存优势，姑息性SC目前是荷兰的标准治疗。 如果 PCI 为 ＜7，则进行胃切除术和 D2 淋巴结清扫术和 CRS，旨在去除所有可见的腹膜疾病，然后进行 HIPEC。 该试验具有重要的局限性。 首先，CT扫描似乎不是评估腹膜疾病程度的最佳诊断工具，在如此严格的PCI临界值（PCI低于或高于7）内。 腹腔 …

2025年2月1日 · Hyperthermic Intraperitoneal Chemoperfusion (HIPEC) is a new adjuvant therapy for the treatment of abdominal malignant tumors and metastases, which has shown great potential.

2025年3月25日 · CRS and HIPEC is performed following the principles first established by Sugarbaker . PCI was calculated at the beginning of the operation to describe the volume and distribution of peritoneal disease, and the completeness of cytoreduction (CC) was recorded at the end of the procedure to describe the macroscopic clearance of visible disease ...

31 Recently, Faron et al studied 180 consecutive patients undergoing CRS and HIPEC for CRC, and observed a linear relationship between PCI and overall survival (OS). They suggested a PCI of 17 as a cutoff for the procedure, as only 7% of patients were alive at 3 years, which was the same for patients undergoing palliative surgery.

2023年4月30日 · The peritoneal cancer index or PCI score is used to quantify the extent of peritoneal cancer spread for pseudomyxoma peritonei (PMP) and other peritoneal surface malignancies. It provides an objective measure of overall tumour burden to help guide treatment decisions and predict prognosis.