PDE3A Gene - GeneCards | PDE3A Protein | PDE3A Antibody
2024年12月25日 · PDE3A (Phosphodiesterase 3A) is a Protein Coding gene. Diseases associated with PDE3A include Hypertension And Brachydactyly Syndrome and Stroke, …
Phosphodiesterase 3 - Wikipedia
The PDE3 family is composed of two genes, PDE3A and PDE3B. In cells expressing both genes, PDE3A is usually dominant. Three different variants of PDE3A (PDE3A1-3) are products of …
磷酸二酯酶(PDEs) - 知乎 - 知乎专栏
pde3有两种基因亚型：pde3a与pde3b,分别位于染色体11与12上，由于起始密码子的不同，pde3a又可分为pde3a1、pde3a2和 pde3a3三种亚型,主要分布于心脏、血小板、血管平滑 …
磷酸二酯酶 - 百度百科
磷酸二酯酶（PDEs）具有水解细胞内第二信使（cAMP,环磷酸腺苷或cGMP,环磷酸鸟苷）的功能，降解细胞内cAMP或cGMP，从而终结这些第二信使所传导的生化作用。 cAMP和cGMP对于 …
磷酸二酯酶 3A（PDE3A）基因 | MCE - MCE-生物活性分子大师
该基因编码 cGMP 抑制的环核苷酸磷酸二酯酶 (cGI-PDE) 家族的成员。 cGI-PDE 酶水解 cAMP 和 cGMP，并通过调节细胞内环核苷酸信号的幅度和持续时间在许多细胞过程中发挥关键作用。 …
Activation of Phosphodiesterase 3A: New Hope for Cardioprotection
2022年12月5日 · In this issue of Circulation, Ercu et al 8 explore the mechanism underlying this phenomenon, uncovering the molecular basis of PDE3A-dependent cardioprotection in the …
【文献分享】PDE3A-SLFN12复合物的结构以及基于该复合物的药 …
基于所获得的PDE3A-SLFN12复合物结构模型与结合模式，作者选用了临床上药代动力学、药效学和安全性都较好的anagrelide作为目标分子进行计算机模拟和进一步优化改造。 结果表明，改 …
5139 - Gene ResultPDE3A phosphodiesterase 3A [ (human)]
PDE3A is a low-affinity and high-velocity enzyme for hydrolysis of cUMP in cardiac myocytes. Chemical proteomics results show that besides known interactors such as 14-3-3 family …
PDE3A phosphodiesterase 3A [ Homo sapiens (human) ]
2020年9月29日 · Title: Identification and functional study of genetic polymorphisms in cyclic nucleotide phosphodiesterase 3A (PDE3A). Nitric oxide activates AMPK by modulating …
Phosphodiesterase 3A Represents a Therapeutic Target that ... - PubMed
PDE3A induced the inflammatory nuclear factor NFκB signaling pathway by suppressing cAMP/PKA, which promotes the expression of the stem cell marker OCT4. In addition, PDE3A …