A phosphodiesterase-4 inhibitor, commonly referred to as a PDE4 inhibitor, is a drug used to block the degradative action of phosphodiesterase 4 (PDE4) on cyclic adenosine …

Phosphodiesterase (PDE) inhibitors are medications that block those enzymes. Some PDE inhibitors are selective, meaning they target a specific type of PDE. Other PDE inhibitors are …

2020年4月20日 · PDE4 inhibitors are a relatively new treatment. They work to suppress the immune system, which reduces inflammation. They act at the cellular level to halt the …

2025年3月4日 · PDE4 inhibitors can be used to treat asthma, chronic obstructive pulmonary disease, psoriasis, atopic dermatitis, inflammatory bowel disease, and rheumatoid arthritis. …

At least four types of the enzyme phosphodiesterase 4 (PDE4) are known: PDE4A; PDE4B; PDE4C; PDE4D

2024年3月6日 · PDE-4 enzymes produce proteins called cytokines, which signal your immune system to get to work. In people with healthy skin, this helps protect against harmful substances.

2013年4月4日 · This review summarizes the development of PDE4 inhibitors and the associated literature with a focus on treatments for autoimmune diseases. After the initial investigations of …

Compare selective phosphodiesterase-4 inhibitors (PDE4). View important safety information, ratings, user reviews, popularity and more.

2023年7月15日 · The inhibition of PDE4 enzymes has been widely investigated as a possible alternative strategy for the treatment of a variety of respiratory diseases, including chronic …

2023年11月30日 · This review summarizes the current knowledge and recent advances in understanding the contribution of the PDE4 subfamily to cardiovascular function and …