A phosphodiesterase-4 inhibitor, commonly referred to as a PDE4 inhibitor, is a drug used to block the degradative action of phosphodiesterase 4 (PDE4) on cyclic adenosine …

Compare selective phosphodiesterase-4 inhibitors (PDE4). View important safety information, ratings, user reviews, popularity and more.

The following is a list of phosphodiesterase inhibitors. This list was created from the NCI Thesaurus.

Compounds that specifically inhibit PHOSPHODIESTERASE 4. A non-steroidal medication used for the treatment of inflammatory conditions such as psoriasis and psoriatic arthritis. …

2022年6月8日 · PDE-4: This type is specific to your lungs, causing muscles in your airway (especially your bronchial tubes) to constrict and tense up. PDE-5: These are in the lungs, and …

2025年3月19日 · Some PDE4 inhibitors help treat chronic obstructive pulmonary disease (COPD), while others help manage eczema, psoriasis, and psoriatic arthritis. These medications work …

The aim of this review was to provide the reader with an overview of PDE4 targeting compounds that have reached clinical trials in the last ten years, since the first PDE4 inhibitor was …

There are four subtypes of PDE4, namely PDE4A–PDE4D, which are highly specific for cAMP degradation but not for cGMP. Inhibition of PDE4 results in the accumulation of intracellular …

Phosphodiesterase-4 (PDE4) inhibitors belong to a class of medications known as disease-modifying anti-rheumatic drugs (DMARDs). PDE4 inhibitors are prescribed to reduce …

2023年3月15日 · Phosphodiesterase 4 (PDE4) hydrolyzes cyclic adenosine monophosphate (cAMP) and plays a vital roles in many biological processes. PDE4 inhibitors have been widely …