
Phosphoinositide-dependent kinase-1 - Wikipedia
PDPK1 is a master kinase, which is crucial for the activation of AKT /PKB and many other AGC kinases including PKC, S6K, SGK. An important role for PDPK1 is in the signaling pathways …
PDK1 Gene - GeneCards | PDK1 Protein | PDK1 Antibody
2024年12月25日 · PDK1 (Pyruvate Dehydrogenase Kinase 1) is a Protein Coding gene. Diseases associated with PDK1 include Pyruvate Dehydrogenase E3-Binding Protein Deficiency and …
PDK-1 (磷酸肌醇依赖性蛋白激酶-1) - MCE-生物活性分子大师
PDK-1 (3-Phosphoinositide-dependent protein kinase 1), a member of the protein A, G and C (AGC) family of proteins, is a Ser/Thr protein kinase. PDK-1, is the pivotal node in the PI3K …
Activation of the essential kinase PDK1 by phosphoinositide …
2022年4月6日 · PDK1 (3-phosphoinositide-dependent kinase 1) is a serine/threonine-protein kinase that plays a central role in regulating cell growth, survival, and proliferation....
丙酮酸脱氢酶激酶 1(PDK1)基因 | MCE - MCE-生物活性 ...
丙酮酸脱氢酶激酶 1: 丙酮酸脱氢酶 (pdh) 是一种线粒体多酶复合物,可催化丙酮酸的氧化脱羧作用,是负责调节哺乳动物碳水化合物燃料稳态的主要酶之一。
PDK1 pyruvate dehydrogenase kinase 1 [ Homo sapiens (human) ]
2025年1月4日 · Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes …
PDK-1 regulates lactate production in hypoxia and is ... - Nature
2008年6月10日 · Here we describe the expression and function of a HIF-1-regulated protein pyruvate dehydrogenase kinase-1 (PDK-1) in head and neck squamous cancer (HNSCC). …
3-磷酸肌醇依赖性蛋白激酶1在肿瘤发生发展及治疗中的作用
3-磷酸肌醇依赖性蛋白激酶1(pdk1)是磷脂酰肌醇3激酶-蛋白激酶b(pi3k-akt)通路的一个关键调节分子。 PDK1可通过激活Akt,参与PI3K-Akt信号通路的活化,促进肿瘤的发生、发展及浸润转移。
丙酮酸脱氢酶激酶 1(Pdk1)基因 | MCE - MCE-生物活性 ...
丙酮酸脱氢酶激酶 1: 该基因编码的蛋白可启动 atp 绑定活动;相同的蛋白质结合活性;和蛋白激酶活性。 参与细胞表面受体信号通路和肽基丝氨酸磷酸化。
PDK-1-生物活性化合物分类 - 化源网
2019年6月28日 · pdk-1在调节细胞迁移中具有重要作用,特别是在pdk-1缺乏的情况下。 PDK-1是有效的治疗靶标,并且表明PDK-1抑制剂可用于预防癌症进展和异常组织传播。 cas号查询
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