PDX1 - Wikipedia
PDX1 (pancreatic and duodenal homeobox 1), also known as insulin promoter factor 1, is a transcription factor in the ParaHox gene cluster. [5] In vertebrates, Pdx1 is necessary for …
PDX1 Gene - GeneCards | PDX1 Protein | PDX1 Antibody
2024年12月25日 · PDX1 (Pancreatic And Duodenal Homeobox 1) is a Protein Coding gene. Diseases associated with PDX1 include Maturity-Onset Diabetes Of The Young, Type 4 and …
摘 要:Pdx1 (pancreatic and duodenal homeobox 1) 是一种同源框转录因子,在胰腺发育及β细胞功能维持中起重要调控作用。 研究发现,Pdx1 基因纯合缺失会导致胰腺发育不全;在β细胞成熟与 …
PDX1 pancreatic and duodenal homeobox 1 [ (human)]
Pdx1 is a transcription factor required for the formation of endocrine pancreas that is inhibited during Coxsackievirus B4 infection of human pancreas ductal cells; recessive PDX1 mutations …
Pdx1-Cre小鼠 - shulb.com
Pdx1-Cre小鼠是一种在胰岛细胞同源框转录因子1（Pancreatic and Duodenal Homeobox 1, Pdx1）基因座插入Cre重组酶的转基因小鼠模型。Pdx1是胰腺发育和β细胞功能的重要调控因 …
PDX1 is the cornerstone of pancreatic β-cell functions and identity
2022年12月14日 · PDX1 is a master regulator in pancreas organogenesis, the maturation and identity preservation of β-cells, and of their role in normal insulin function.
PDX1 是胰腺 β 细胞功能和特性的基石,Frontiers in ... - X-MOL
2022年12月15日 · pdx1 是胰腺器官发生、β 细胞的成熟和特性保存以及它们在正常胰岛素功能中的作用的主要调节因子。 PDX1 基因突变与许多胰腺功能障碍相关，包括胰腺发育不全（纯合 …
pdx1通过与胰岛素启动子区的特定dna序列结合 来反式激活胰岛素,pdx1活性的降低可能是导致 t2dm中胰岛β细胞失调的关键。成人正常的胰岛 功能需要pdx1,pdx1减少会影响葡萄糖传递和 …
PDX-1 (pancreatic/duodenal homeobox-1 protein 1) - PubMed
It has been shown that PDX-1 is required for maintaining pancreatic islet functions by activating gene expression and has a dual role in pancreatic development. It initially contributes to …
PDX-1的基因表达及调节 - 国际内分泌代谢杂志 - Yiigle.com
胰腺十二指肠同源盒1 (PDX-1),是目前较公认的胰腺干细胞的特异性标志,是胰腺分化发育关键的转录因子.PDX-1基因的活化可促进胰岛素、生长抑素、葡萄糖激酶等胰腺β细胞重要基因的表达, …