2023年1月18日 · Herein, we walk the reader through correct interpretation of 1 H NMR spectra of functionalized PEG. Carbon satellite peaks observed in 1 H NMR spectra are due to the 1.1% natural abundance of 13 C, an NMR active nucleus with spin 1/2 that couples with directly bonded non-equivalent 1 H nuclei, splitting the 1 H peak.

2003年5月17日 · We synthesized a library of 50 poly (ethylene glycol) (PEG) derivatives to expand the extent of conjugation with biologically active molecules (biopolymers, peptides, drugs, etc.) and biomaterial substrates. The formation of PEG derivatives was …

2023年1月18日 · ABSTRACT: The molecular weight, purity, and functionalization of polyethylene glycols are often characterized by 1H NMR spectroscopy. Oft-forgotten, the typical 1H NMR pulse sequence is not 13C decoupled.

1990年8月1日 · In the present work we show that proton NMR spectra of PEGs dissolved in deuterated dimethyl sulfoxide (but not other solvents) reveal a hydroxyl peak at 4.56 (±0.02) ppm, which does not shift...

2012年5月25日 · In this study, a star-shaped 4-arm PEG molecule that contained different kinds of functional groups at its ends was synthesized using DY as the fluorescent core. Depending on the nature of the PEG molecules linked to DY, various types of 4-arm PEG could be synthesized.

2023年1月18日 · The molecular weight, purity, and functionalization of polyethylene glycols are often characterized by 1H NMR spectroscopy. Oft-forgotten, the typical 1H NMR pulse sequence is not 13C decoupled.

2023年1月18日 · The molecular weight, purity, and functionalization of polyethylene glycols are often characterized by 1 H NMR spectroscopy. Oft-forgotten, the typical 1 H NMR pulse sequence is not 13 C decoupled. Hence, for large polymers, the 13 C coupled 1 H peak …

聚乙二醇（peg）脂质纳米颗粒（lnp）在水中自发组装，形成均匀大小的纳米颗粒，与单独使用药物的血液清除率相比，具有更长的血液清除率。以前，通过物理和分子相结合的方法来分析1,2-二硬脂酰-sn-甘油-3-磷酸乙醇胺-n- [甲氧基（聚乙二醇）-2000]（dspe-peg 2000）和几种药物加合物，包括阿霉素动态 ...

The molecular weight, purity, and functionalization of polyethylene glycols are often characterized by 1H NMR spectroscopy. Oft-forgotten, the typical 1H NMR pulse sequence is not 13C decoupled. Hence, for large polymers, the 13C coupled 1H peaks ...

如果你的NMR是做完的产物，我想应该是你在反应时羟基没有完全反应，你可以对比一下买来的PEG2000单甲醚的NMR谱图. 1.84是不会有峰的，至少我的PEG2000单甲醚的核磁在这个位置没有，端羟基的说法靠不住，端基会很小很小的峰的，不会这么明显。 看看你的核磁试剂是否有污染，而且PEO容易吸潮，干燥一下再测试吧. 我就是怀疑可能是水峰，因为我是在冰乙醚中析出抽滤的，又没有除水操作（除了真空干燥），PEG又吸水，没有水峰是说不过去的，但是没有证据 …