
Pathology Outlines - Peutz-Jeghers polyp
2023年4月10日 · Peutz-Jeghers polyp is a hamartomatous polyp associated with Peutz-Jeghers syndrome that is characterized by papillary architecture with arborizing compact bundles of smooth muscle
Peutz-Jeghers Syndrome: What It Is, Symptoms & Genetics
2023年7月26日 · Peutz-Jeghers syndrome (PJS) is a benign (noncancerous) genetic condition that causes you to develop polyps in your GI tract. It increases your cancer risk.
Peutz–Jeghers syndrome - Wikipedia
Peutz–Jeghers syndrome (often abbreviated PJS) is an autosomal dominant genetic disorder characterized by the development of benign hamartomatous polyps in the gastrointestinal tract and hyperpigmented macules on the lips and oral mucosa (melanosis). [2] This syndrome can be classed as one of various hereditary intestinal polyposis syndromes [3] and one of various hamartomatous polyposis ...
Peutz-Jeghers Syndrome - StatPearls - NCBI Bookshelf
2023年7月17日 · Peutz-Jeghers syndrome (PJS) is a hereditary cancer syndrome characterized by gastrointestinal (GI) polyposis, mucocutaneous pigmented macules, and cancer predisposition. Patients with Peutz-Jeghers syndrome are at an increased risk for developing GI cancers of the colorectal, pancreatic, and gastric organs, in addition to a wide variety of non-GI epithelial malignancies such as breast ...
Peutz-Jeghers polyp - Libre Pathology
2018年4月25日 · Peutz-Jeghers polyp, abbreviated PJP, is an uncommon hamartomous gastrointestinal polyp. It is usually associated with Peutz-Jeghers syndrome.
三、如何診斷黑斑息肉症候群? 可根據其皮膚粘膜黑色素沉著、胃腸道多發息肉及家族史這三大臨床特點而得到診斷,符合以下 其中一點即可診斷5。 1. 組織學上確認有兩個或更多的缺陷瘤(hamartomatous polyps) 2. 有PJ syndrome家族史 + 任何數量的缺陷瘤(hamartomatous polyps) 3.
Peutz-Jeghers syndrome: a critical look at colonic Peutz-Jeghers polyps …
2012年9月17日 · Peutz-Jeghers syndrome is an autosomal dominant condition characterized by gastrointestinal hamartomatous polyps. The pathologic identification of a Peutz-Jeghers polyp is integral to the diagnosis of this syndrome that often remains undiagnosed until after these polyps are identified. Histologically, Peutz-Jeghers polyps are characterized by a distinctive arborization of smooth muscle within ...
Solitary Peutz-Jeghers polyp harboring a focus of high-grade
2024年11月13日 · A solitary Peutz-Jeghers (PJ) polyp is a rare hamartomatous lesion without an associated PJ syndrome. However, little is known regarding malignancy arising in solitary PJ polyps. Here, we report a case of a solitary colonic PJ polyp with focal dysplasia. A 45-year-old asymptomatic man underwent tota …
The Management of Peutz–Jeghers Syndrome: European …
Solitary PJ polyps are rare, but there are numerous case reports describing the identification of a solitary PJ polyp, which may occur at all sites of the gastrointestinal tract, with the exception of the esophagus.
Genetic and epigenetic profiling of a solitary Peutz-Jeghers colon polyp
A rare subtype of colon polyps is the Peutz-Jeghers (PJ) polyp. PJ polyps mostly occur in the context of Peutz-Jeghers syndrome, which is characterized by the development of multiple polyps in the intestinal tract and hyperpigmentation of oral mucosa and lips.
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