Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary kidney disorder, affecting approximately one in 500 births. It is characterized by focal development and progressive enlargement of renal cysts, typically leading to …

Imaging is an important approach to diagnosis, monitoring and predicting outcomes for patients with Autosomal Dominant polycystic Kidney Disease (ADPKD). This paper reviews three common clinical imaging techniques, ultrasonography, computed tomography (CT), magnetic resonance imaging (MRI) and their role in management of ADPKD.

2024年7月31日 · Autosomal dominant polycystic kidney disease is one of the most common serious hereditary diseases, found in 1:400 to 1:1000 individuals, and is by far the most common inherited cause of end-stage renal failure (ESRF) 6. It accounts for 4-10% of all cases of ESRF 6. Several conditions are well recognized as being associated with ADPKD 1,3,5,6:

Autosomal dominant polycystic kidney disease (ADPKD) is the most common form of cystic disease, with a frequency of 1 in 800 live births and is caused by mutations in the PKD1 gene on chromosome 16 or the PKD2 gene on chromosome 4 .

Individuals who are at risk for autosomal dominant polycystic kidney disease are often screened by ultrasound using diagnostic criteria derived from individuals with mutations in PKD1. Families with mutations in PKD2 typically have less severe disease, suggesting a potential need for different diagn …

Autosomal dominant polycystic kidney disease (ADPKD) is the most common life-threatening hereditary disease in the United States, occurring in approximately one in every 400 to 1000 live births. 1 ADPKD accounts for approximately 5 to 10% of end-stage renal failure in the United States requiring dialysis and renal transplantation. 2 ADPKD is ...

This article reviews three common clinical imaging techniques, ultrasonography, computed tomography, magnetic resonance imaging, and their role in the management of autosomal-dominant polycystic kidney disease. Ultrasonographic criteria for …

2022年4月27日 · Total kidney volume (TKV) is the most important imaging biomarker for quantifying the severity of autosomal-dominant polycystic kidney disease (ADPKD). 3D ultrasound (US) can accurately measure kidney volume compared to 2D US; however, manual segmentation is tedious and requires expert annotators.

Health professionals providing information on testing should have a clear understanding of the benefits and challenges of USS or genetic testing for ADPKD. We recommend that children and young people aged 5 years and above with, or at risk of developing ADPKD, should have an assessment of blood pressure (BP) at least once every 2 years. (B)

2020年5月1日 · Autosomal dominant polycystic kidney disease (ADPKD) is an inherited multisystem disorder, characterized by progressive cystic enlargement of the kidneys. Considered as the fourth leading cause of ESKD in the United States it is noted for kidney (e.g., hypertension, progressive, CKD, fibrosis), as well as extra-kidney manifestations.