RANKL/RANK signaling (WP2018) - Homo sapiens | WikiPathways
Binding of RANKL to RANK triggers downstream signaling events that leads to the activation of osteoclasts and controlling of lineage commitment. RANKL/RANK signaling is essential for …
Phospholipase Cγ1 (PLCγ1) Controls Osteoclast Numbers via …
2017年1月1日 · PLCγ1 effects on the OCs are different compared with PLCγ2, which is activated in response to RANKL. Clarifying the exact roles of PLCγ1 and PLCγ2 in the regulation of …
Plcg1 phospholipase C, gamma 1 [ (house mouse)] - National …
2025年2月8日 · Plcg1 signalling regulates lipopolysaccharide-induced Ptgs2 protein expression in cardiomyocytes. Plcg1 potentiates integrin-dependent cell spreading and migration through …
Expression of PLCγ1 and PLCγ2 during B-cell development and …
Phospholipase Cgamma1 (PLCgamma1) has been reported to be expressed predominantly in T cells and to play an important role in T-cell receptor signaling. Here we show that PLCgamma1 …
磷脂酶 Cγ1（PLCG1）基因 | MCE - MCE-生物活性分子大师
该基因编码的蛋白质催化磷脂酰肌醇 4,5-二磷酸形成肌醇 1,4,5-三磷酸和甘油二酯。 该反应使用钙作为辅助因子，并在受体介导的酪氨酸激酶激活剂的细胞内转导中发挥重要作用。 例如，当 …
Lyn inhibits osteoclast differentiation by interfering with PLCgamma1 ...
2009年4月2日 · The forced reduction of Lyn caused a striking increase in the RANKL-induced PLCgamma1, Ca(2+), and NFATc1 responses during differentiation. These data suggest that …
Plcg1 - phospholipase C, gamma 1 基因 | MCE - MCE-生物活性分 …
Enables glutamate receptor binding activity; phosphatidylinositol Phospholipase C activity; and receptor tyrosine kinase binding activity. Involved in modulation of chemical synaptic …
PLCG1 Gene - GeneCards | PLCG1 Protein | PLCG1 Antibody
2024年12月25日 · PLCG1 (Phospholipase C Gamma 1) is a Protein Coding gene. Diseases associated with PLCG1 include Immune Dysregulation, Autoimmunity, And Autoinflammation …
PLCγ1：癌症进展的潜在仲裁者。,Advances in Biological …
PLCγ1是PLC的主要亚型之一，可直接被膜受体激活，包括受体酪氨酸激酶（RTK）和粘附受体（例如整联蛋白）。 PLCγ1通过与其他信号分子通过SH结构域直接相互作用来介导信号传 …
Recent advances in understanding the molecular role of …
2021年12月1日 · Phospholipase C gamma 1 (PLCγ1) which belongs to phosphoinositide-specific phospholipase C (PLC) family, is activated by many extracellular stimuli including hormones, …