
Proteolipid protein cannot replace P0 protein as the major ...
The central nervous system (CNS) of terrestrial vertebrates underwent a prominent molecular change when proteolipid protein (PLP) replaced P0 protein as the most abundant protein of …
Proteolipid protein modulates preservation of peripheral ...
Here we show that the abundance of PLP but not of other tetraspan myelin proteins is strongly increased in compact peripheral myelin of P0 (null)-mice. To determine the functional …
Human myelin proteolipid protein structure and lipid bilayer ...
PLP is a 30-kDa integral membrane protein mainly expressed by CNS oligodendrocytes. Minor expression can be observed in PNS myelin, as well as in kidney distal and proximal tubules . …
Proteolipid Protein Is Necessary in Peripheral as Well as ...
1997年7月1日 · The intriguing phylogenetic analyses of P0, DM20, and PLP by Yoshida and Colman 1996 demonstrate that PLP/DM20 is present in PNS compact myelin of teleosts and …
Proteolipid protein cannot replace P0 protein as the major ...
To investigate the possible consequences of a PLP to P 0 shift in PNS myelin, we engineered mice to express PLP instead of P 0 in PNS myelin (PLP-PNS mice). PLP-PNS mice had …
Structure and expression of proteolipid protein in the ...
Steady-state levels of PLP mRNA in SC cultures treated with the cAMP analogue dibutyryl cAMP (dBcAMP) were not increased, whereas dBcAMP increased steady-state levels of mRNA …
Proteolipid protein cannot replace P0 protein as the major ...
2014年7月28日 · The central nervous system (CNS) of terrestrial vertebrates underwent a prominent molecular change when proteolipid protein (PLP) replaced P 0 protein as the most …
18823 - Gene ResultPlp1 proteolipid protein (myelin) 1 ...
2025年2月8日 · axonal mitochondria, smooth endoplasmic reticulum, and microtubules were characterized in rodent optic nerves where PLP is replaced by the peripheral nerve myelin …
Concomitant expression of proteolipid protein (PLP) and P0 in ...
Concomitant expression of proteolipid protein (PLP) and P0 in remyelinating cerebral lesion (index case 1). (A) The peripheral nerve from case 4 was stained with an antibody to P0 (green) and …
Plasmolipin and Its Role in Cell Processes - PMC
PLLP is involved in intracellular transport, lipid raft formation, and Notch signaling. PLLP is presumably involved in various disorders, such as cancer, schizophrenia, Alzheimer’s disease, …