
Periplogenin attenuates LPS-mediated inflammatory osteolysis …
2024年2月17日 · This study found that Ppg prevented LPS-induced skull osteolysis by inhibiting the expression of inflammatory cytokines and osteoclast production. In vitro, Ppg blocked the …
IF:7.0!中科院2区!中药提取化合物治疗炎性骨病新思路 - 知乎
本研究提出Ppg通过抑制炎性细胞因子的表达和破骨细胞的产生来预防LPS诱导的炎性骨溶解,从而成为治疗炎症性骨溶解的一种新疗法。 体外实验证明Ppg阻断RANKL诱导的破骨细胞的产 …
Periplogenin attenuates LPS-mediated inflammatory osteolysis …
2024年2月17日 · This study found that Ppg prevented LPS-induced skull osteolysis by inhibiting the expression of inflammatory cytokines and osteoclast production. In vitro, Ppg blocked the …
Leishmania major proteophosphoglycan is expressed by …
1999年7月1日 · Proteophosphoglycan (PPG) is a newly described mucin-like glycoprotein found on the surface of Leishmania major promastigotes and secreted in the culture supernatant. We …
Periplogenin 通过减少 NF-κB 和 MAPK 信号通路抑制破骨细胞生成,从而减轻 LPS …
在体内,Ppg 减少了骨骼表面破骨细胞的数量,并抑制了 LPS 诱导的颅骨骨溶解。 这些结果表明 Ppg 可以作为一种新的替代疗法,通过抑制炎症和破骨细胞来治疗炎症性骨溶解。
H2S alleviated sepsis-induced acute kidney injury by inhibiting …
2024年11月1日 · After inhibiting CSE activity with dl-propargylglycine (PPG i. p.), the renal tissue pathology in LPS-induced AKI mice was further exacerbated, leading to enhanced activation of …
(PDF) Periplogenin attenuates LPS-mediated inflammatory …
2023年7月20日 · This study found that Ppg prevented LPS-induced skull osteolysis by inhibiting the expression of inflammatory cytokines and osteoclast production. In vitro, Ppg blocked the …
Periplogenin attenuates LPS-mediated inflammatory osteolysis …
This study found that Ppg prevented LPS-induced skull osteolysis by inhibiting the expression of inflammatory cytokines and osteoclast production. In vitro, Ppg blocked the RANKL-induced …
Effects of CCK-8 and Cystathionine γ-Lyase/Hydrogen Sulfide
2016年11月24日 · Herein, we concluded that CCK-8 alleviated the ALI induced by LPS via regulating the catalytic activity of cystathionine γ-lyase (CSE) and the formation of H 2 S. This …
This study found that Ppg prevented LPS-induced skull osteolysis by inhibiting fl the expression of inammatory cytokines and osteoclast production. In vitro, Ppg blocked the RANKL-induced...