Polysialylated-neural cell adhesion molecule (PSA-NCAM) in …
Nov 6, 2008 · The polysialylated form of the cell surface glycoprotein neural cell adhesion molecule (PSA-NCAM) is a dynamically regulated product of post-translational modification of …
The PSA-NCAM-Positive “Immature” Neurons: An Old Discovery …
One of the first molecules used in studies on CNS structural plasticity, including adult neurogenesis, was the polysialylated form of the neural cell adhesion molecule (PSA-NCAM) …
PSA-NCAM: an important regulator of hippocampal plasticity
The Neural Cell Adhesion Molecule (NCAM) serves as a temporally and spatially regulated modulator of a variety of cell-cell interactions. This review summarizes recent results of studies …
神经可塑性标志物 PSA-NCAM：洞察促进神经再生的 ... - X-MOL
作为发育和成人神经可塑性的主要贡献者，神经细胞粘附分子 (psa-ncam) 的多唾液酸化形式可能被证明是促进 cns 损伤和疾病后修复/再生的潜在目标。 多年来，已经开发了几种实验方法来 …
PSA-NCAM in mammalian structural plasticity and neurogenesis
Polysialic acid (PSA) is a linear homopolymer of alpha2-8-N acetylneuraminic acid whose major carrier in vertebrates is the neural cell adhesion molecule (NCAM). PSA serves as a potent …
The neuroplasticity marker PSA-NCAM: Insights into new …
Oct 1, 2020 · Polysialic acid (PSA) is a linear glycopolymer consisting of multiple α2,8-linked N -acetylneuraminic acid units that are attached to the neural cell adhesion molecule (NCAM) as …
The neuroplasticity marker PSA-NCAM: Insights into new …
Being the central contributor to the developmental and adult neuroplasticity, the polysialylated form of Neural Cell Adhesion Molecule (PSA-NCAM) may prove to be a potential target to …
PSA–NCAM: Synaptic functions mediated by its interactions with ...
Apr 1, 2012 · Dynamic regulation of glycosylation of the neural cell adhesion molecule (NCAM) by an unusual large negatively charged polysialic acid (PSA) is the major prerequisite for correct …
PSA–NCAM Is Required for Activity-Induced Synaptic Plasticity
Treatment of the cultures with endoneuraminidase-N selectively removed polysialic acid (PSA) from NCAM and completely prevented induction of long-term potentiation (LTP) and long-term …
Nuclear fragments of the neural cell adhesion molecule NCAM …
Oct 19, 2017 · Here, we show that the nuclear import of the PSA-carrying NCAM fragment is mediated by positive cofactor 4 and cofilin, which we identified as novel PSA-binding proteins. …
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