Pregnancy-specific beta-1-glycoprotein 5 is a protein that in humans is encoded by the PSG5 gene. [3] [4]

The pSG5 Vector is a eukaryotic expression vector constructed by combining pKCR2 and the Agilent pBS vector. Because of the high copy number of this plasmid, large quantities of double-stranded DNA are obtained. Applications . The pSG5 is …

2024年12月25日 · PSG5 (Pregnancy Specific Beta-1-Glycoprotein 5) is a Protein Coding gene. Diseases associated with PSG5 include Gestational Trophoblastic Neoplasm and Androgen Insensitivity Syndrome. Among its related pathways are Response to elevated platelet cytosolic Ca2+ and Cell surface interactions at the vascular wall.

Strong synergic activity of KLF4 and Sp1 on the PSG-5 promoter. The human pregnancy-specific glycoproteins (PSGs) are a group of molecules that are mainly produced by the placental syncytiotrophoblasts during pregnancy. PSGs comprise a subgroup of the carcinoembryonic antigen (CEA) family, which belongs to the immunoglobulin superfamily.

This mini-review describes the generation and application of the pSG5 vector family, highlighting the specific features of the distinct vector plasmids. Keywords: CRISPR/Cas9; Mobilization; Plasmid; Stable replication; Streptomyces.

2024年4月3日 · show that human PSG1 binds alphaIIbbeta3 and inhibits the platelet - fibrinogen interaction. Unexpectedly, however, the KGD is not critical as multiple PSG1 domains independently bind and inhibit alphaIIbbeta3 function. Title: Pregnancy-specific glycoproteins bind integrin αIIbβ3 and inhibit the platelet-fibrinogen interaction.

2010年11月2日 · We now provide the "Disease & Variants" viewer in its own tab. The viewer provides 705 variants from UniProt as well as other sources including ClinVar and dbSNP. Go to variant viewer. Showing features for signal, chain, glycosylation, disulfide bond. Synthesized by syncytiotrophoblast of the placenta.

The PSG subfamily contains at least 11 different genes. For 7 of these, two DNA sequences differing from each other in 1 to 4 nucleotides were detected. Most likely, they represent different alleles. They are PSG1, PSG2, PSG3, PSG4, PSG5, PSG6, PSG7, PSG8, PSG11, PSG12, and PSG13. Six of the N-domain sequences described here are new.

2013年2月13日 · Pharmacological inhibition of histone deacetylases (HDACs) up-regulated PSG protein and mRNA expression levels, and augmented the amount of acetylated histone H3 associated with PSG 5′regulatory regions.

The Agilent pSG5 Expression Vector is a 4.1 KB eukaryotic expression vector that enables large quantities of double-stranded DNA to be obtained due to high copy number. It is suitable for use for in vivo or in vitro expression.