2015年8月8日 · The translational GTPase BipA regulates the expression of virulence and pathogenicity factors in several eubacteria. BipA-dependent expression of virulence factors …

A double bipA-uup deletion has a more severe growth phenotype, low 70S ribosomes but higher amounts of 50S ribosomal subunits than the single bipA deletion. The growth phenotype is …

2020年9月9日 · Here we show that E. coli Δ bipA cells grown at suboptimal temperature accumulate immature large subunit particles missing several proteins. These include L17 and …

2008年12月1日 · We isolated and characterized suppressors of the cold-sensitive growth phenotype exhibited by Δ bipA strains and identified insertion mutations in rluC. The rluC gene …

2020年9月4日 · Here we show that Escherichia coli ΔbipA cells grown at suboptimal temperature accumulate immature large subunit particles missing several proteins. These include L17 and …

2015年8月21日 · A conformational change of BipA upon ppGpp binding could explain the ppGpp regulation of the binding specificity of BipA. Here, we present the structures of the full-length …

2020年9月4日 · Here we show that Escherichia coli ΔbipA cells grown at suboptimal temperature accumulate immature large subunit particles missing several proteins. These include L17 and …

2015年8月21日 · To discern the molecular mechanism of regulation of BipA, we determined the effect of ppGpp binding on the molecular structure of BipA by x-ray crystallography, isothermal …

Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.

BPI-inducible protein A (BipA), a highly conserved paralog of the well-known translational GTPases LepA and EF-G, has been implicated in bacterial motility, cold shock, stress …