ssGSEA2.0/PTM-SEA - GitHub
PTM-Signature Enrichment Analysis (PTM-SEA) is a modified version of ssGSEA to perform site-specific signature analysis by scoring PTMsigDB's bi-directional signature-sets. The input to …
PTM-SEA分析 - 景杰生物 | 磷酸化修饰相关特征富集分析
景杰生物提供PTM-SEA（PTM-Signature Enrichment Analysis）分析服务，通过磷酸化位点识别信号通路的失调，进行特征富集分析，为疾病机制、医疗诊断和药物研发提供重要参考。
ssGSEA2.0/PTM-SEA - GitHub
Single sample Gene Set Enrichment analysis (ssGSEA) and PTM Enrichment Analysis (PTM-SEA) Resources
A Curated Resource for Phosphosite-specific Signature Analysis
We adapted the widely used single sample Gene Set Enrichment Analysis approach to utilize PTMsigDB, enabling PTM S ignature E nrichment A nalysis (PTM-SEA) of quantitative MS …
Cell新风向 | 泛癌翻译后修饰分析揭示蛋白质调节共同模式 - 知乎
分析时，作者重点关注树状图中的顶部分裂，应用了位点特异性通路富集分析—ptm-sea，以及基于底物特异性预测ptm调节因子的激酶库（star方法中的ptm专用工具），两种工具均显示，在 …
刘文教授团队发文Nature子刊揭示基于蛋白质组学的食管癌分子分 …
2021年8月26日 · PTM-SEA 分析发现， CDK1 、 CDK2 、 CDC7 、 CHEK2 和 MELK 等 kinase-substrate signatures 显著上调，为食管癌的靶向治疗提供了候选靶点。此外，与食管癌已知的 …
Kim Phan / ssGSEA2-0 - GitLab
2021年4月16日 · Single sample Gene Set Enrichment analysis (ssGSEA) and PTM Enrichment Analysis (PTM-SEA)
PTMsigDB - Database Commons - National Genomics Data Center
We adapted the widely used single sample Gene Set Enrichment Analysis approach to utilize PTMsigDB, enabling ignature nrichment nalysis (PTM-SEA) of quantitative MS data. We used …
A Curated Resource for Phosphosite-specific Signature Analysis
2019年3月1日 · PTM signature enrichment analysis (PTM-SEA) outperformed gene-centric analysis in detection of EGF induced phospho signaling events. PI3K perturbation signatures …
Post-translational modification-centric base editor screens to …
2024年4月29日 · Here we describe the high-throughput, functional assessment of phosphorylation sites through the development of PTM-centric base editing coupled to phenotypic screens, …
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