... evaluate the therapeutic efficacy of Tf-Glu-PTX and its potential cytotoxicity, cell viability assays were carried out in cancer cells (MCF7) and normal cells (293T). The results in Fig. 4A...

2014年6月15日 · Paclitaxel (PTX) is a first-line antineoplastic drug that is commonly used in clinical chemotherapy for breast cancer treatment. However, the occurrence of drug resistance …

PAMAM-PTX, GE-PAMAM-PTX, PAMAM and PTX was evaluated by 3-(4,5-dimethylthiazol-2-Yl)-2,5-diphenyltetrazolium bromide (MTT) assay using 293T cell lines. In vitro cellular uptake …

2021年12月5日 · The prodrug BTMP-SS-PTX and its control substance BTMP-CC-PTX were synthesized. More outstanding anticancer activity in Hep G2, MCF-7 and HeLa cells, lower …

Then the chemotherapeutic drugs, such as PTX, the ncRNAs, such as miR-551-3p, immune molecules, such siPDL1, were released into the tumor microenvironment (TME). Thereafter, …

2021年8月6日 · Purpose: To develop and evaluate paclitaxel (PTX) loaded pegylated gelatin targeted nanoparticles for improved efficacy in non-small cell lung cancer (NSCLC) treatment. …

目的：开发肽-树状聚合物-紫杉醇偶联物，用于治疗293t和l132细胞系中的异种1期非小细胞肺癌（nsclc）。方法：采用nhs方法制备树状大分子-紫杉醇共轭物（pamam-ptx），并用于合成 …

Phase-contrast microscopy images of untreated 293T cells (A), 293T cells treated with DMSO only (B), and 293T cells treated with 5 nM PTX (C), 10 nM PTX (D), 50 nM PTX (E) and 100 nM...

2017年5月4日 · Purpose: To develop peptide-dendrimer-paclitaxel conjugates for the treatment of heterogeneous stage 1 non small cell lung cancer (NSCLC) in 293T and L132cell line. …

2017年5月4日 · Purpose: To develop peptide-dendrimer-paclitaxel conjugates for the treatment of heterogeneous stage 1 non small cell lung cancer (NSCLC) in 293T and L132cell line. …