
Paxillin - Wikipedia
Paxillin is a protein that in humans is encoded by the PXN gene. Paxillin is expressed at focal adhesions of non-striated cells and at costameres of striated muscle cells, and it functions to …
桩蛋白 - 百度百科
Paxillin 是一种涉及胞外基质细胞黏附(黏着斑)位点上肌动蛋白-膜附着的细胞骨架蛋白。 Paxillin 在整合蛋白的信号传导中起着非常重要的作用,整合蛋白介导的细胞骨架的再组织需要 …
Paxillin and focal adhesion signalling - Nature Cell Biology
Paxillin is a multi-domain adaptor found at the interface between the plasma membrane and the actin cytoskeleton. Here it provides a platform for the integration and processing of...
PLoS新研究:整合素与细胞内蛋白paxillin相互作用的关键
2024年9月7日 · 其中一种重要的蛋白质是paxillin。由于paxillin存在于所有细胞中,作为整合素与细胞骨架之间的桥梁,它也成为可视化黏着斑的标志。
Paxillin: a crossroad in pathological cell migration | Journal of ...
2017年2月18日 · Paxilllin is a multifunctional and multidomain focal adhesion adapter protein which serves an important scaffolding role at focal adhesions by recruiting structural and …
PXN Gene - GeneCards | PAXI Protein | PAXI Antibody
2024年12月25日 · PXN (Paxillin) is a Protein Coding gene. Diseases associated with PXN include Papilloma and Prostate Cancer. Among its related pathways are Cell junction organization and …
Paxillin: a crossroad in pathological cell migration - PMC
Paxilllin is a multifunctional and multidomain focal adhesion adapter protein which serves an important scaffolding role at focal adhesions by recruiting structural and signaling molecules …
Paxillin comes of age - PMC
Paxillin is a multi-domain scaffold protein that localizes to the intracellular surface of sites of cell adhesion to the extracellular matrix. Through the interactions of its multiple protein-protein …
Paxillin - PubMed
Paxillin is a 68 kDa cytoplasmic protein that localizes to discrete sites of cell attachment to the extracellular matrix called focal adhesions. It is a multi-domain adapter protein capable of …
Paxillin: a focal adhesion-associated adaptor protein - PubMed
2001年10月1日 · Paxillin is a focal adhesion-associated, phosphotyrosine-containing protein that may play a role in several signaling pathways. Paxillin contains a number of motifs that …
Paxillin: a focal adhesion-associated adaptor protein
2001年10月17日 · Paxillin is a focal adhesion-associated, phosphotyrosine-containing protein that may play a role in several signaling pathways. Paxillin contains a number of motifs that …
Paxillin - SpringerLink
2017年1月1日 · Paxillin is an approximately 68-kDa multi-domain adapter protein featuring 5 LD motifs and 4 LIM domains. It is mainly a cytoplasmic protein enriched at focal adhesions in …
Paxillin family of focal adhesion adaptor proteins and
The paxillin family of proteins, including paxillin, Hic-5, and leupaxin, are focal adhesion adaptor/scaffolding proteins which localize to cell-matrix adhesions and are important in cell …
Paxillin S273 Phosphorylation Regulates Adhesion Dynamics and …
2019年8月7日 · Phosphorylation of the focal adhesion adaptor protein, paxillin, on serine 273 (S273) has been implicated as a key regulator of cell migration. Here, it is shown that …
Paxillin and Kindlin: Research Progress and Biological Functions
Paxillin and kindlin are essential regulatory proteins involved in cell adhesion, migration, and signal transduction. Paxillin influences cytoskeletal dynamics by interacting with multiple …
Paxillin: a crossroad in pathological cell migration - PubMed
2017年2月18日 · Paxilllin is a multifunctional and multidomain focal adhesion adapter protein which serves an important scaffolding role at focal adhesions by recruiting structural and …
Paxillin comes of age - PMC - National Center for Biotechnology …
2008年8月1日 · In this brief review of paxillin’s formative years, from its humble origins as a structural “peg”, we have focused primarily on highlighting advances in our understanding of …
Paxillin Actions in the Nucleus - PMC - National Center for ...
Paxillin and its family members are complex proteins that play major roles in modulating signaling throughout cells. When paxillin is outside the nucleus, it functions to modulate cell-cell …
The structure and functions of paxillin and its roles in ...
Paxillin is an important cell scaffold and cellular signaling protein, especially a key molecule of the Integrin-mediated downstream signaling transduction. This review summarizes the structure …
Diverse Roles for the Paxillin Family of Proteins in Cancer
The paxillin family of intracellular scaffold proteins includes paxillin, Hic-5, and leupaxin, and all have been identified as key regulators of the cellular migration machinery in both 2- and 3 …