Paxillin is a protein that in humans is encoded by the PXN gene. Paxillin is expressed at focal adhesions of non-striated cells and at costameres of striated muscle cells, and it functions to …

Paxillin 是一种涉及胞外基质细胞黏附（黏着斑）位点上肌动蛋白-膜附着的细胞骨架蛋白。 Paxillin 在整合蛋白的信号传导中起着非常重要的作用，整合蛋白介导的细胞骨架的再组织需要 …

Paxillin is a multi-domain adaptor found at the interface between the plasma membrane and the actin cytoskeleton. Here it provides a platform for the integration and processing of...

2024年9月7日 · 其中一种重要的蛋白质是paxillin。由于paxillin存在于所有细胞中，作为整合素与细胞骨架之间的桥梁，它也成为可视化黏着斑的标志。

2017年2月18日 · Paxilllin is a multifunctional and multidomain focal adhesion adapter protein which serves an important scaffolding role at focal adhesions by recruiting structural and …

2024年12月25日 · PXN (Paxillin) is a Protein Coding gene. Diseases associated with PXN include Papilloma and Prostate Cancer. Among its related pathways are Cell junction organization and …

Paxilllin is a multifunctional and multidomain focal adhesion adapter protein which serves an important scaffolding role at focal adhesions by recruiting structural and signaling molecules …

Paxillin is a multi-domain scaffold protein that localizes to the intracellular surface of sites of cell adhesion to the extracellular matrix. Through the interactions of its multiple protein-protein …

Paxillin is a 68 kDa cytoplasmic protein that localizes to discrete sites of cell attachment to the extracellular matrix called focal adhesions. It is a multi-domain adapter protein capable of …

2001年10月1日 · Paxillin is a focal adhesion-associated, phosphotyrosine-containing protein that may play a role in several signaling pathways. Paxillin contains a number of motifs that …

2001年10月17日 · Paxillin is a focal adhesion-associated, phosphotyrosine-containing protein that may play a role in several signaling pathways. Paxillin contains a number of motifs that …

2017年1月1日 · Paxillin is an approximately 68-kDa multi-domain adapter protein featuring 5 LD motifs and 4 LIM domains. It is mainly a cytoplasmic protein enriched at focal adhesions in …

The paxillin family of proteins, including paxillin, Hic-5, and leupaxin, are focal adhesion adaptor/scaffolding proteins which localize to cell-matrix adhesions and are important in cell …

2019年8月7日 · Phosphorylation of the focal adhesion adaptor protein, paxillin, on serine 273 (S273) has been implicated as a key regulator of cell migration. Here, it is shown that …

Paxillin and kindlin are essential regulatory proteins involved in cell adhesion, migration, and signal transduction. Paxillin influences cytoskeletal dynamics by interacting with multiple …

2017年2月18日 · Paxilllin is a multifunctional and multidomain focal adhesion adapter protein which serves an important scaffolding role at focal adhesions by recruiting structural and …

2008年8月1日 · In this brief review of paxillin’s formative years, from its humble origins as a structural “peg”, we have focused primarily on highlighting advances in our understanding of …

Paxillin and its family members are complex proteins that play major roles in modulating signaling throughout cells. When paxillin is outside the nucleus, it functions to modulate cell-cell …

Paxillin is an important cell scaffold and cellular signaling protein, especially a key molecule of the Integrin-mediated downstream signaling transduction. This review summarizes the structure …

The paxillin family of intracellular scaffold proteins includes paxillin, Hic-5, and leupaxin, and all have been identified as key regulators of the cellular migration machinery in both 2- and 3 …