Pre-B cell colony enhancing factor (PBEF) is regarded as a proinflammatory cytokine. Named for its first discovered function as a pre-B cell colony enhancing factor, it has since been found to have many other functions relating to cell metabolism, inflammation, and …

Nicotinamide phosphoribosyltransferase (NAmPRTase or NAMPT), formerly known as pre-B-cell colony-enhancing factor 1 (PBEF1) or visfatin for its extracellular form (eNAMPT), [5] is an enzyme that in humans is encoded by the NAMPT gene. [6] .

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Pre-B cell colony-enhancing factor (PBEF) has been shown to have a variety of biological functions. Studies have proven that PBEF plays a functional role in acute lung injury (ALI). Therefore, in this study, we aimed to confirm the importance of PBEF in ALI.

B前细胞集落增强因子（PBEF）也称为Nampt / visfatin，是一种多效性52 kDa细胞因子样分子，其活性与多种炎症性疾病有关。PBEF通过抑制本构性PMN凋亡来促进多形核中性粒细胞（PMN）促炎功能。我们调查了PBEF是否激活或引发PMN呼吸爆发。

Background: Nicotinamide phosphoribosyltransferase (NAMPT), also known as pre-B-cell colony-enhancing factor (PBEF) or visfatin, has been reported to be a crucial factor involved in tumor metabolism, angiogenesis and cell apoptosis. However, its definite roles in patients with malignant cancer remain unclear.

Pre-B Cell Colony Enhancing Factor (PBEF) is a stress-responsive cytokine expressed by the human amnion, and is known to induce Vascular Endothelial Growth Factor (VEGF) production by other cell types. Interestingly, VEGF is up-regulated in the ovine amnion when intramembranous absorption is augmented.

2016年8月31日 · We previously demonstrated that Pre-B-cell colony-enhancing factor (PBEF), also known as nicotinamide phosphoribosyltransferase (NAMPT), the rate-limiting enzyme in mammalian NAD + biosynthesis...

In this study, we investigated the effects of visfatin/PBEF on RASFs in detail, with the main focus specifically on the change in gene and protein expression mediated by visfatin/PBEF, signaling pathways involved in these processes, and alterations in fibroblast motility to further clarify the role of visfatin/PBEF in RA.

Pre-B cell colony enhancing factor (PBEF) is regarded as a proinflammatory cytokine. Named for its first discovered function as a pre-B cell colony enhancing factor, it has since been found to have many other functions relating to cell metabolism, ...