Aggresome assembly at the centrosome is driven by CP110
2022年4月11日 · Super-resolution imaging and colocalization analysis revealed that protein aggregates (pHSP27, Ub + and p62), satellite proteins (PCM1 and PIBF1) and CP110 occupy …
PCM1 antibody (19856-1-AP) | Proteintech | 武汉三鹰生物技术有 …
Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 19856-1-AP (PCM1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with …
Counterregulation of cAMP-directed kinase activities controls ...
2018年3月26日 · PCM1 is also a target of the ubiquitin-proteasome system (UPS). In growing cells, ubiquitylation of PCM1, AZI1, and CEP290 by the E3 ligase MIB1 suppresses primary …
Centrosomes grow aggresomes to clear waste - Nature Cell Biology
2022年4月11日 · Centrosomes are membrane-free organelles comprised of a pair of cylindrical structures (centrioles) embedded in a protein-rich matrix (PCM), which is the site of …
PCM1 Gene - GeneCards | PCM1 Protein | PCM1 Antibody
2024年12月25日 · PCM1 (Pericentriolar Material 1) is a Protein Coding gene. Diseases associated with PCM1 include Differentiated Thyroid Carcinoma and Thyroid Cancer, …
Deubiquitylase USP9X maintains centriolar satellite integrity by ...
2019年1月1日 · In this study, we find that the deubiquitylase USP9X binds PCM1, and antagonizes PCM1 ubiquitylation to protect it from proteasomal degradation. Knockdown of …
(PDF) Aggresome assembly at the centrosome is driven by …
2022年4月1日 · Protein degradation is critical to maintaining cellular homeostasis, and perturbation of the ubiquitin proteasome system leads to the accumulation of protein …
Association of PCM1 with the E3 ubiquitin ligases MIB1 and …
Download scientific diagram | Association of PCM1 with the E3 ubiquitin ligases MIB1 and WWP2. Co-localization of (A) PCM1 (red) with MIB1 (green) and (B) PCM1 (red) with WWP2 (green) …
周围物质 1（PCM1）基因 | MCE - MCE-生物活性分子大师
Chromosomal aberrations involving this gene are associated with papillary thyroid carcinomas and a variety of hematological malignancies, including atypical chronic myeloid leukemia and …
PCM1：与肺腺癌免疫浸润相关的潜在预后生物标志物 - X-MOL
2023年12月8日 · 背景：最近的研究证实了中心粒周材料 1 (PCM1) 在几种恶性肿瘤细胞系中的作用，但其在肺腺癌 (LUAD) 中的具体生物学功能仍不清楚。 目的：为了解决这一差距，本研究 …