
增殖细胞核抗原(PCNA)的特点和意义 - 知乎
2023年12月25日 · 抗PCNA抗体 是抗增殖细胞核抗原抗体,抗PCNA抗体阳性指体内存在针对细胞核中抗原物质所产生的一种自身抗体,与一些疾病有关,如 系统性红斑狼疮 和肿瘤细胞, …
Proliferating cell nuclear antigen - Wikipedia
Proliferating cell nuclear antigen (PCNA) is a DNA clamp that acts as a processivity factor for DNA polymerase δ in eukaryotic cells and is essential for replication.
Proliferating cell nuclear antigen (PCNA): a key factor in DNA ...
Proliferating cell nuclear antigen (PCNA) is an evolutionarily well-conserved protein found in all eukaryotic species as well as in Archaea. PCNA was first shown to act as a processivity factor …
Human PCNA Structure, Function, and Interactions - PMC
Proliferating cell nuclear antigen (PCNA) is an essential factor in DNA replication and repair. It forms a homotrimeric ring that embraces the DNA and slides along it, anchoring DNA …
Proliferating cell nuclear antigen (PCNA): a key factor in DNA ...
PCNA exerts a tripartite function by operating as (1) a sliding clamp during DNA synthesis, (2) a polymerase switch factor and (3) a recruitment factor. Most of its functions are mediated by its …
PCNA Gene - GeneCards | PCNA Protein | PCNA Antibody
2024年12月25日 · PCNA (Proliferating Cell Nuclear Antigen) is a Protein Coding gene. Diseases associated with PCNA include Ataxia-Telangiectasia-Like Disorder 2 and Actinic Keratosis. …
PCNA: structure, functions and interactions - PubMed
2001年1月1日 · Proliferating cell nuclear antigen (PCNA) plays an essential role in nucleic acid metabolism as a component of the replication and repair machinery. This toroidal-shaped …
PCNA is an essential component of the DNA replication machin-ery, functioning as the accessory protein for DNA polymerase d (Pold), required for processive chromo-somal DNA synthesis, …
Something’s gotta give: How PCNA alters its structure in response …
2021年8月1日 · Proliferating cell nuclear antigen (PCNA) is an essential protein that regulates the systematic recruitment and activity of proteins in a multitude of biochemical processes. Very …
PCNA cycling dynamics during DNA replication and repair in …
2024年6月1日 · Proliferating cell nuclear antigen (PCNA) is a eukaryotic replicative DNA clamp that plays multiple roles during chromosome duplication and damaged DNA repair. After the …