2024年12月25日 · PCSK1N (Proprotein Convertase Subtilisin/Kexin Type 1 Inhibitor) is a Protein Coding gene. Diseases associated with PCSK1N include Parkinsonism and Breast Lipoma. …

2025年1月4日 · Gene ID: 27344, updated on 4-Jan-2025. The protein encoded by this gene functions as an inhibitor of prohormone convertase 1, which regulates the proteolytic cleavage …

2025年1月4日 · The protein encoded by this gene functions as an inhibitor of prohormone convertase 1, which regulates the proteolytic cleavage of neuroendocrine peptide precursors. …

Specifically expressed in neuroendocrine tissue and brain. Main subcellular location based on data generated in the subcellular section of the Human Protein Atlas. Manually selected …

这个基因编码的蛋白质作为前激素转换酶1的抑制剂发挥作用，调节神经内分泌肽前体的蛋白水解切割。 前蛋白进一步加工成多个短肽。 这个基因内的多态性可能与肥胖症有关。 …

PCSK1N is likely to be part of the adaptive response to ER stress, potentially conferring a survival advantage to the corticotroph tumor cell in conjunction with other proteins. PCSK1N is higher …

neuronal proSAAS plays an important role in proteostatic processes. Cloning of proSAAS homologs in Danio and Xenopus identifies conserved, putatively functional areas. ProSAAS or …

该基因编码枯草杆菌蛋白酶样原蛋白转化酶家族的一个成员，其中包括通过分泌途径的受调节或组成性分支处理蛋白质和肽前体运输的蛋白酶。 编码的蛋白质在 ER 中经历初始自催化处理事 …

2024年12月25日 · PCSK1 (Proprotein Convertase Subtilisin/Kexin Type 1) is a Protein Coding gene. Diseases associated with PCSK1 include Proprotein Convertase 1/3 Deficiency and …

关于 pcsk1n Cytogenetic location: Xp11.23 Genomic coordinates (GRCh38): X:48,831,096-48,835,610 (from NCBI) This gene has 2 transcripts (splice variants) and 78 orthologues.