2024年2月20日 · Despite considerable efforts to identify human liver cancer genomic alterations that might unveil druggable targets, the systematic translation of multiomics data remains challenging. Here, we report success in long-term culture of 64 patient-derived hepatobiliary tumor organoids (PDHOs) from a Chinese population.

2024年1月26日 · 本研究，我们报告了来自中国人群的 64 个患者来源的肝胆肿瘤类器官 （pdho） 的长期培养结果。 观察到其对 265 种代谢和表观遗传学相关化学物质和 36 种抗癌药物的不同反应。

1997年旅德回国创办了第二军医大学国际合作生物信号转导研究中心和东方肝胆外科医院综合治疗病区，建成首个肝癌生物样本库，形成基础与临床结合的创新研究基地。 [5] 创新研发了新的肝癌诊断试剂，获国内外发明专利和国家食药监总局批复的医疗器械证书，在临床广泛应用推广；发现抑癌基因影响胆道肿瘤的新机制，建立了新的分子分型方法指导老药新用；发现新的癌基因、抑制性受体和肠道菌群对肝癌的调控机制，为肝癌防治提供了新的靶标；发现非编码RNA在肝癌、 …

主要从事恶性肿瘤的基础与临床研究，包括肝胆肿瘤发病机制，细胞炎-癌转化分子机理、细胞信号转导网络调控、肿瘤功能基因组学和肿瘤代谢，以及肿瘤早期诊断标志物的研发。...

PdHO in Healthcare commonly refers to Pediatric Hematology-Oncology, which is a specialized field focused on diagnosing and treating blood disorders and cancers in children. Explore categories such as Medical and Healthcare for more information.

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2024年1月25日 · Here, we report success in long-term culture of 64 patient-derived hepatobiliary tumor organoids (PDHOs) from a Chinese population. A divergent response to 265 metabolism- and epigenetics-related chemicals and 36 anti-cancer drugs is observed.

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Pepakura is a very popular piece of software for translating a 3d model into a series of paper elements that can be printed and cut out, to rebuild said model. Unfortunately, it's Windows …