Identification and Comparison of Receptor Binding Characteristics …
2016年2月23日 · The N-terminal domain (NTD) of the PEDV S1 domain could bind sugar, a possible co-receptor for PEDV. The prototype strain exhibited weaker sugar-binding activity …
The glycosylation sites in RBD of spike protein attenuate the ...
2024年7月1日 · In this study, three recombinant PEDVs were engineered to evaluate the effects of glycosylation in RBD on the pathogenicity and immunogenicity of PEDV. The glycosylation …
鉴定猪流行性腹泻病毒纤突蛋白受体结合区（PEDV-RBD）重组蛋 …
2024年6月24日 · 利用杆状病毒表达系统制备猪流行性腹泻病毒（pedv）纤突蛋白受体结合区（rdb）重组蛋 白（pedv-rdb），将其免疫3周龄断乳仔猪，分析其免疫原性。 将PEDV …
The glycosylation sites in RBD of spike protein attenuate the ...
Porcine epidemic diarrhea (PED) is a highly contagious swine intestinal disease caused by PED virus (PEDV). Vaccination is a promising strategy to prevent and control PED. Previous …
PEDV: Insights and Advances into Types, Function, Structure, and ...
In 2015, Liu expressed the S1 RBD fragment and pAPN [102,103] and showed by dot blot hybridization that the PEDV S1 subunit binds effectively to pAPN. In addition, pseudovirus …
猪δ冠状病毒与猪流行性腹泻病毒的受体结合区融合表达及免疫原 …
This study aims to develop an effective bivalent subunit vaccine that is promising to prevent both porcine deltacoronavirus (PDCoV) and porcine epidemic diarrhea virus (PEDV). The receptor …
In situ structure and dynamics of an alphacoronavirus spike …
2022年8月19日 · Porcine epidemic diarrhea (PED) is a highly contagious swine disease caused by porcine epidemic diarrhea virus (PEDV). PED causes enteric disorders with an...
猪流行性腹泻mRNA疫苗的制备与免疫原性评价
本研究选择pedv rbd作为疫苗靶抗原，制备了基于rbd单体和二聚体的mrna疫苗，并在小鼠和妊娠母猪上评价了候选疫苗的免疫原性，证明单次免疫即可诱导良好的免疫应答，而且与活疫苗配 …
猪流行性腹泻病毒纤突蛋白受体结合区 (PEDV-RBD)重组蛋白的免 …
摘要：利用杆状病毒表达系统制备猪流行性腹泻病毒 (porcine epidemic diarrhea virus,PEDV)纤突蛋白受体结合区 (receptor binding domain,RBD)重组蛋白 (PEDV-RBD),将其免疫3周龄断乳仔 …
猪流行性腹泻病毒纤突蛋白受体结合区(PEDV-RBD)重组蛋白的免 …
利用杆状病毒表达系统制备猪流行性腹泻病毒(porcine epidemic diarrhea virus,PEDV)纤突蛋白受体结合区(receptor binding domain,RBD)重组蛋白(PEDV-RBD),将其免疫3周龄断乳仔猪,分析 …
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